• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Surgical Endoscopy >Patient-centered measures for achalasia.
【24h】

Patient-centered measures for achalasia.

机译：以患者为中心的门失弛缓症措施。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Various instruments may be used to measure health-related quality of life in patients with achalasia. METHODS: We administered four patient-centered measures used for evaluation of achalasia severity [an achalasia severity questionnaire we developed previously, an achalasia symptom checklist, the Gastrointestinal Quality-of-Life Index (GIQLI), and the Medical Outcomes Study 36-item Short-Form survey (SF-36)] to 25 subjects enrolled in a randomized controlled trial comparing pneumatic dilatation and laparoscopic Heller myotomy. We estimated correlations between the different measures. RESULTS: Twenty-five patients (13 male, 12 female) were studied; 12 were treated by pneumatic dilatation and 13 by laparoscopic myotomy. The average age of patients was 48.5 [range 25-69, standard deviation (SD) 13.7] years. Baseline scores demonstrated a substantial burden of impairment. The mean (SD) score on the achalasia severity measure [ranges from 0 (best) to 100 (worst)] was 62.3 (13.4). The mean (SD) symptom checklist score [ranges from 0 (best) to 36 (worst)] was 23.2 (6.6). The mean (SD) GIQLI [ranges from 0 (worst) to 144 (best)] was 77.04 (19.4). The SF-36 mean (SD) for the physical component score (PCS) was 45.29 (9.21) and the mean for the mental component score (MCS) was 37.61 (14.97). The achalasia severity measure correlated highly with the GIQLI (r = -0.57, p = 0.01), and the symptom checklist (r = 0.65, p = 0.004). The achalasia severity measure correlated well with the SF-36 PCS (r = -0.42, p = 0.039), but not with the MCS (r = -0.14, p = 0.501). CONCLUSION: Subjects recruited to a randomized controlled trial of achalasia treatment demonstrated impairment in both generic quality-of-life and disease-specific measures. Scores on achalasia-specific measures correlated well with each other, but less well with measures of generic quality-of-life and mental health scales. Because of the multidimensional nature of achalasia, disease-specific measures should be combined with generic health measures for the best assessment of patient outcome.
机译：背景：各种仪器可用于测量门失弛缓患者的健康相关生活质量。方法：我们采用了四种以患者为中心的措施，用于评估门失弛缓的严重程度[我们之前开发的门失弛缓严重程度调查表，an门失弛缓症状清单，胃肠道生活质量指数（GIQLI）和医学成果研究36项形式调查（SF-36）]对25位受试者进行了一项随机对照试验，比较了气管扩张术和腹腔镜Heller肌切开术。我们估计了不同度量之间的相关性。结果：25例患者（男13例，女12例）进行了研究。气管扩张术治疗12例，腹腔镜肌切开术治疗13例。患者的平均年龄为48.5 [范围25-69，标准差（SD）13.7]年。基线分数显示出很大的损伤负担。失弛缓症严重程度测量的平均（SD）评分[从0（最佳）到100（最差）]为62.3（13.4）。平均（SD）症状检查清单评分[范围从0（最佳）到36（最差）]为23.2（6.6）。平均值（SD）GIQLI [范围从0（最差）到144（最佳）]为77.04（19.4）。 SF-36身体成分评分（PCS）的平均值（SD）为45.29（9.21），精神成分评分（MCS）的平均值为37.61（14.97）。门失弛缓的严重程度与GIQLI（r = -0.57，p = 0.01）和症状清单（r = 0.65，p = 0.004）高度相关。门失弛缓的严重程度与SF-36 PCS密切相关（r = -0.42，p = 0.039），而与MCS无关（r = -0.14，p = 0.501）。结论：接受门失弛缓症治疗的随机对照试验的受试者表现出一般生活质量和疾病特异性措施的损害。特定于门失弛缓症措施的得分相互关联良好，但与一般生活质量和精神健康量表的得分关联性较低。由于门失弛缓症的多维性质，应将针对疾病的措施与一般健康措施相结合，以最好地评估患者的预后。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号