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首页> 外文期刊>Surgical Endoscopy >Primary malignant melanoma of the esophagus: a case report.
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Primary malignant melanoma of the esophagus: a case report.

机译：食道原发性恶性黑色素瘤：一例报告。

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Primary malignant melanoma of the esophagus is an uncommon tumor associated with a poor survival (5% at 5 years), even when resected at an early stage. Because its symptoms are no different from those of other malignant tumors of the esophagus, histopathologic examination is usually needed to reach a definitive diagnosis. A 57-year-old white nonsmoking nonalcoholic woman was referred to our department after 2 months of increasing dysphagia, odynophagia, and weight loss (5 kg in 2 months). Esophagogastroscopy revealed a dark blue, pediculated, polypoid lesion. Biopsies were taken. Endoscopic ultrasound showed a hyperechoic heterogeneous tumor. Barium esophagogram showed a filling defect of ~ 6 cm in the middle-low esophagus, and thoracic and abdominal computed tomography (CT) scan showed a well-delimited esophageal tumor with no clear lymph node enlargement. The pathology report described a proliferation of small spindle-shaped or stellate cells arranged in a spiral or fascicular structure. All tumor cells were intensively positive for immunoreaction, using HMB45 antimelanoma antibodies. To remove the tumor, distal esophagectomy through a double abdominal and thoracic approach was performed. No postoperative complications were reported and no chemo- or radiotherapy was given. The patients is still alive with no evidence of recurrence at 9 months after the operation.
机译：食管原发性恶性黑色素瘤是一种罕见的肿瘤，即使在早期切除，其生存率也很差（5年时为5％）。由于其症状与食道的其他恶性肿瘤相同，因此通常需要进行组织病理学检查才能明确诊断。吞咽困难，吞咽困难和体重减轻（2个月内5公斤）增加2个月后，一名57岁的白人非吸烟非酒精性女性被转介到我科。食管胃镜检查显示为深蓝色，有蒂的息肉样病变。进行活检。内镜超声检查显示为高回声异质性肿瘤。钡餐食管造影显示中下食道有约6 cm的充盈缺损，胸部和腹部CT扫描显示食管肿瘤界限清楚，淋巴结未见明显肿大。病理报告描述了呈螺旋形或束状结构排列的小纺锤形或星状细胞的增殖。使用HMB45 anlanlanoma抗体，所有肿瘤细胞均强烈免疫应答阳性。为了切除肿瘤，通过双腹部和胸腔入路进行了远端食管切除术。没有术后并发症的报道，也没有进行化学或放射治疗。术后9个月，患者仍然活着，没有复发的迹象。

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