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Palliative antecolic isoperistaltic gastrojejunostomy: A randomized controlled trial comparing open and laparoscopic approaches

机译:姑息性前肠胃全胃空肠吻合术:比较开放和腹腔镜方法的随机对照试验

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摘要

Gastric outlet obstruction is a common, often preterminal, event for patients with inoperable neoplasms of the distal stomach, duodenum, and biliopancreatic area. It can be surgically managed by open or laparoscopic gastrojejunostomy. This study aimed to compare the results of open and laparoscopic palliative gastrojejunostomy for patients with gastric outlet obstruction resulting from inoperable neoplasms. A total of 24 patients were randomized prospectively to undergo laparoscopic (12 patients) or open (12 patients) palliative laterolateral antecolic isoperistaltic gastrojejunostomy. All the procedures were completed as planned. The mean duration of surgery was not significantly different between the two groups (p = 0.75). The mean intraoperative blood loss was significantly less after laparoscopic gastrojejunostomy (LGJ) (p = 0.0001). Time to oral solid food intake was longer after open gastrojejunostomy (OGJ) (p = 0.04). Two patients in the OGJ group experienced postoperative delayed gastric empting, whereas no patients in the LGJ group experienced such a complication (p = 0.04). The mean postoperative stay was shorter in the LGJ group, but the difference did not reach statistical significance (p = 0.65). No readmissions were registered after a minimum follow-up period of 2 months. The findings show that LGJ is a safe, feasible, and effective alternative to OGJ. However, because the current data involved only a small number of patients, large studies still are required for further evaluation of the this operation's effectiveness. 2006 Springer Science+Business Media, Inc.
机译:对于远端胃,十二指肠和胆胰区域无法手术的肿瘤患者,胃出口阻塞是常见的,通常是终末期事件。可以通过开放式或腹腔镜胃空肠吻合术进行手术治疗。这项研究的目的是比较开放性和腹腔镜姑息性胃空肠吻合术治疗因无法手术的肿瘤而导致胃出口梗阻的患者的结果。前瞻性将总共24例患者随机接受腹腔镜(12例)或开放性(12例)姑息性外侧外侧前庭等速胃空肠吻合术。所有程序均按计划完成。两组的平均手术时间无明显差异(p = 0.75)。腹腔镜胃空肠吻合术(LGJ)后平均术中失血量明显减少(p = 0.0001)。开放性胃空肠吻合术(OGJ)后口服固体食物的摄入时间更长(p = 0.04)。 OGJ组中的两名患者术后出现胃排空延迟,而LGJ组中没有患者发生过这种并发症(p = 0.04)。 LGJ组的平均术后住院时间较短,但差异没有统计学意义(p = 0.65)。至少随访2个月后没有再次入院。研究结果表明,LGJ是OGJ的安全,可行和有效的替代方案。但是,由于当前数据仅涉及少数患者,因此仍需要进行大量研究才能进一步评估该手术的有效性。 2006年Springer Science + Business Media,Inc.

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