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首页> 外文期刊>Surgical Endoscopy >Improvement of restrictive and obstructive pulmonary mechanics following laparoscopic bariatric surgery.
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Improvement of restrictive and obstructive pulmonary mechanics following laparoscopic bariatric surgery.

机译：改善腹腔镜减肥手术后的限制性和阻塞性肺力学。

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BACKGROUND: Morbidly obese patients often have impaired respiratory mechanics leading to restrictive and obstructive lung diseases. Weight loss after bariatric surgery has been shown to improve or resolve many obesity-related comorbidities. However, few studies have examined long-term changes in pulmonary mechanics after bariatric surgery. We hypothesize that pulmonary function improves after surgically induced weight loss. METHODS: We examined the pulmonary function of 104 morbidly obese patients who underwent laparoscopic gastric bypass or gastric banding. Pulmonary studies, including forced expiratory volume in 1 s (FEV(1)), forced vital capacity (FVC), peak expiratory flow (PEF), and forced expiratory volume at midexpiratory phase (FEV(25-75%)) were measured preoperatively and at 3-month intervals. All results are expressed as a percentage of the baseline values. RESULTS: There were 80 females and 24 males with a mean age of 41 years. The mean body mass index was 48 kg/m(2). The mean percentage of excess body weight loss at 12 months was 54%. At 12 months postoperatively, restrictive pulmonary mechanics significantly improved as demonstrated by an increase in the FEV(1) to 112% of baseline value, increase in the FVC to 109% of baseline value, increase in the PEF to 115% of baseline value, and increase in the FEV(25-75%) to 130% of baseline value. Additionally, the percentage of patients with obstructive lung pattern (FEV(1)/FVC ratio less than 0.8) decreased from 9.6% preoperatively to 1.9% postoperatively (p=0.03). CONCLUSIONS: Weight loss after laparoscopic gastric bypass significantly improves restrictive and obstructive respiratory mechanics. The improvements were observed as early as 3 months postoperatively.
机译：背景：病态肥胖的患者经常呼吸系统功能受损，导致限制性和阻塞性肺部疾病。减肥手术后的体重减轻已被证明可以改善或解决许多肥胖相关的合并症。但是，很少有研究检查减肥手术后肺力学的长期变化。我们假设手术诱发的体重减轻后肺功能得到改善。方法：我们检查了104名接受腹腔镜胃旁路手术或胃束带病的肥胖病患者的肺功能。术前测量肺部研究，包括1 s内的强制呼气量（FEV（1）），强制肺活量（FVC），峰值呼气流量（PEF）和呼气中期中的强制呼气量（FEV（25-75％））。并且每三个月间隔一次。所有结果均以基线值的百分比表示。结果：平均年龄为41岁，女性80例，男性24例。平均体重指数为48 kg / m（2）。 12个月时，多余体重减轻的平均百分比为54％。术后12个月，限制性肺力学显着改善，表现为FEV（1）增加到基线值的112％，FVC增加到基线值的109％，PEF增加到基线的115％，并将FEV（25-75％）增加到基线值的130％。此外，阻塞性肺部疾病（FEV（1）/ FVC比值小于0.8）的患者百分比从术前的9.6％降至术后的1.9％（p = 0.03）。结论：腹腔镜胃旁路手术后的体重减轻显着改善了限制性和阻塞性呼吸力学。术后3个月即可观察到改善。

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