...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Surgical Endoscopy >Laparoscopic colorectal surgery and vascular endothelial growth factor.
【24h】

Laparoscopic colorectal surgery and vascular endothelial growth factor.

机译：腹腔镜大肠手术与血管内皮生长因子的关系。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The paper "Persistent elevation of plasma VEGF levels during the first month following minimally invasive colorectal resection" increases our understanding of the impact that surgery has on the complex universe of tissue-derived growth factors, which are critical for wound healing but also have an impact on various malignant tumors. The "dark side" of these healing factors, of which there are several classes, is that overexpression, at least theoretically, can promote the implantation or growth of metastatic cancers. Vascular endothelial growth factor (VEGF) is one of the most potent and well studied of the tissue-derived angiogenic factors, and as such has been closely investigated, particularly for its role in tumor implantation and growth. One of the most important recent chemotherapeutic developments for colon cancer, in fact, has been antiangiogenic therapy, and drugs such as the recombinant humanized anti-VEGF monoclonal antibody bevacizumab are rapidly becoming an important element in chemotherapeutic regimens for advanced colon cancers.
机译：论文“微创结直肠癌切除术后第一个月血浆VEGF水平持续升高”增加了我们对手术对组织衍生生长因子的复杂影响的理解，这对于伤口愈合至关重要，但也有影响在各种恶性肿瘤上。这些治愈因子的“阴暗面”（分为几类）是至少在理论上过表达可以促进转移性癌症的植入或生长。血管内皮生长因子（VEGF）是组织衍生的血管生成因子中作用最强且研究最深入的一种，因此已进行了深入研究，尤其是其在肿瘤植入和生长中的作用。实际上，最近对于结肠癌最重要的化学治疗进展之一就是抗血管生成治疗，诸如重组人源化抗VEGF单克隆抗体贝伐单抗的药物正迅速成为晚期结肠癌化学治疗方案中的重要元素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号