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首页> 外文期刊>Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer >Surgical and other invasive approaches to recurrent pleural effusion with malignant etiology.
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Surgical and other invasive approaches to recurrent pleural effusion with malignant etiology.

机译:复发性胸腔积液的外科手术及其他侵入性治疗,病因恶变。

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With an increasing number of cancer survivors, the annual incidence of malignant pleural effusions has been rising in recent decades worldwide. Many patients with various forms of cancer develop malignant pleural effusions at some point in their life. Patients most commonly present with progressive dyspnea. These effusions are refractory and are associated with impaired quality of life for these patients. The main goals of management are evacuation of the pleural fluid and prevention of its re-accumulation. The therapy plan should consider the general health of the patients, their performance status, the presence of trapped lung, and the primary malignancy. However, there is no universally established, standard approach. Surgical options include thoracentesis, chest tube drainage, thoracoscopy followed by chemical and mechanical pleurodesis, Pleur-X catheter drainage, and pleurectomy. Chemical pleurodesis is the most common modality of therapy for patients with recurrent pleural effusion. For example, Talc is the most successful pleurodesis agent with similar equal to that of poudrage or slurry. Pleur-X catheter can reduce hospital stay and adds value to the treatment of patients with trapped lung, who are not appropriate candidates for pleurodesis. Furthermore, a mechanical pleurodesis has been shown to be effective particularly in pleural effusions with lower pH. This article reviews the surgical and other invasive options as well as their technical aspects in the management of recurrent malignant pleural effusions.
机译:随着癌症幸存者数量的增加,最近几十年来,全球恶性胸腔积液的年发病率一直在上升。许多患有各种形式癌症的患者在其生命中的某个时候会发生恶性胸腔积液。患者最常出现进行性呼吸困难。这些积液是难治性的,并与这些患者的生活质量受损有关。管理的主要目标是排空胸膜液并防止其再次积聚。治疗计划应考虑患者的总体健康状况,他们的表现状况,肺部受困情况以及原发性恶性肿瘤。但是,还没有普遍建立的标准方法。手术选择包括胸腔穿刺术,胸腔引流,胸腔镜检查,然后进行化学和机械性胸膜固定术,Pleur-X导管引流术和胸膜切除术。化学胸膜固定术是复发性胸腔积液患者最常见的治疗方法。例如,滑石粉是最成功的胸膜固定剂,其类似于胶凝剂或浆液。 Pleur-X导管可以减少住院时间,并为不适合进行胸膜固定术的肺困患者的治疗增加价值。此外,已经显示机械胸膜固定术尤其在具有较低pH的胸腔积液中是有效的。本文回顾了复发性恶性胸腔积液的外科治疗和其他侵入性选择及其技术方面。

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