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首页> 外文期刊>Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer >Exploring physical activity level in patients with thoracic cancer: implications for use as an outcome measure.
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Exploring physical activity level in patients with thoracic cancer: implications for use as an outcome measure.

机译：探索胸癌患者的体力活动水平：作为结果指标的意义。

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Cachexia is common in patients with thoracic cancer impairing physical function and quality of life. New approaches which target muscle tissue are emerging and activity monitors could provide an objective assessment of their effect on physical function. We have collated data from three studies involving the use of one such monitor in order to benchmark aspects of physical activity for patients with thoracic cancer, explore how these relate to physician-rated performance status, and consider the implications for future studies.Patients with thoracic cancer and an Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 0-2 wore an ActivPAL? monitor for 1 week. The mean time spent each day in a range of activities, e.g. standing or stepping, or their frequency, e.g. number of sit-to-stand transitions, steps taken, were calculated and compared according to ECOG PS.Data from 84 patients (54 male; mean (SD) age, 66 (9) years) were collated. Each day, patients spent a mean (SD) of 4.3 (2.0) h upright, completed 45 (17) sit-to-stand transitions and took 4,246 (2,983) steps. There was wide variation in each activity examined. All but the number of sit-to-stand transitions differed significantly between ECOG PS categories.These data provide a detailed insight into how physical activity levels decline across the range of ECOG PS categories studied. The wide variation in physical activity within each ECOG PS category suggests that this scale may lack sufficient sensitivity to evaluate new cachexia treatments. Our data help to inform future work in this area.
机译：恶病质在胸癌损害身体功能和生活质量的患者中很常见。针对肌肉组织的新方法正在兴起，活动监测器可以提供对其对身体功能影响的客观评估。我们整理了三项研究的数据，其中涉及使用一台这样的监测器，以对胸癌患者的身体活动进行基准测试，探讨这些行为与医师评估的表现状态之间的关系，并考虑对未来研究的影响。癌症且东部合作肿瘤小组绩效状态（ECOG PS）为0-2时是否佩戴了ActivPAL？监控1周。每天在一系列活动中花费的平均时间，例如站立或踩踏或其频率，例如根据ECOG PS计算并比较了从坐到站的过渡次数，采取的步骤。整理了84位患者（54位男性;平均（SD）年龄，66（9）岁）的数据。每天，患者直立平均花费（SD）为4.3（2.0）小时，完成了45（17）个从站到站的过渡，并采取了4,246（2,983）个步骤。所检查的各项活动差异很大。在ECOG PS类别之间，除了从站到站的过渡次数外，其他所有类别均存在显着差异。每个ECOG PS类别的体育活动差异很大，表明该量表可能缺乏足够的敏感性来评估新的恶病质治疗。我们的数据有助于为该领域的未来工作提供信息。

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