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Diagnostically Challenging 'Fatty' Retroperitoneal Tumors

机译:诊断上具有挑战性的“肥大”腹膜后肿瘤

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摘要

A variety of benign and malignant retroperitoneal mesenchymal lesions may have a component of adipose tissue, including entities such as lipoma, myolipoma, angiomyolipoma, solitary fibrous tumor, genital stromal tumors, and well-differentiated/dedifferentiated liposarcoma. Although definitive diagnosis is usually straightforward on the complete resection specimen, it is often more difficult to workup these lesions on small biopsy samples. This review focuses on challenging diagnostic scenarios of retroperitoneal lesions with a "fatty" component and provides major differential diagnoses for commonly encountered morphologic patterns, clinicopathologic features of the various entities, and strategy for use of ancillary techniques, such as immunohisto-chemistry and cytogenetic studies.
机译:腹膜后间质的各种良性和恶性病变可能是脂肪组织的一部分,包括诸如脂肪瘤,肌脂瘤,血管平滑肌瘤,孤立性纤维瘤,生殖器基质肿瘤和分化良好/去分化的脂肪肉瘤等实体。尽管在完整切除标本上通常可以直接进行明确的诊断,但是在较小的活检样本上对这些病变进行检查通常更为困难。这篇综述着重于具有“脂肪”成分的腹膜后病变的具有挑战性的诊断情况,并为常见的形态学模式,各种实体的临床病理特征以及使用辅助技术(例如免疫组织化学和细胞遗传学研究)的策略提供了主要的鉴别诊断。 。

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