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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Initial clinical experience with a new self-retaining left ventricular lead for permanent left ventricular pacing.
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Initial clinical experience with a new self-retaining left ventricular lead for permanent left ventricular pacing.

机译：新型自固定式左心室导线用于永久性左心室起搏的初步临床经验。

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This study evaluated the performance of a new lead for permanent left ventricular (LV) pacing via the coronary sinus (CS) in four men and nine women (mean age = 71 +/- 13 years) with sick sinus syndrome. It consists of a 75-cm-long, 4.8-Fr, unipolar ventricular lead with a distal portion preshaped in an S curve to provide steerability and stability within the CS. Its efficacy and stability for permanent LV pacing were tested at implant, predischarge, and at 1, 3 and 6 months of follow-up. The lead was successfully implanted in 11/13 patients (85%) within a mean fluoroscopy time of 35 +/- 22 minutes. The final positions of the electrodes at the tip of the lead within venous tributaries of the CS were: (1) anterior (n = 2, 18%); (2) posterolateral (n = 5, 45%); and (3) the lateral (n = 4, 36%). Unsuccessful implants were due to unstable lead position (n = 1), or high pacing threshold (n = 1). There was no postprocedural lead dislodgment or significant changes in the R wave amplitude, LV pacing threshold and lead impedance up to 6 months of follow-up. In summary, this initial experience suggests that this new lead offers safe and reliable permanent LV pacing via the CS in the majority of patients and may be used in isolation or in conjunction with right ventricular pacing for biventricular synchronization.
机译：这项研究评估了在患有病窦综合征的四名男性和九名女性（平均年龄= 71 +/- 13岁）中通过冠状窦（CS）进行永久性左心室（LV）起搏的新导线的性能。它由一条长75厘米，4.8英尺的单极心室导线组成，其远端部分预成型为S形曲线，以在CS内提供可操纵性和稳定性。在植入，预放电以及1、3和6个月的随访中测试了其对永久性LV起搏的有效性和稳定性。在平均荧光检查时间35 +/- 22分钟内，将铅成功植入了11/13例患者（占85％）。在CS的静脉支流中，导线尖端的电极的最终位置为：（1）前侧（n = 2，18％）; （2）后外侧（n = 5，45％）; （3）侧面（n = 4，36％）。植入失败是由于不稳定的引线位置（n = 1）或高起搏阈值（n = 1）。术后6个月内，术后无铅移位或R波幅度，LV起搏阈值和铅阻抗无明显变化。总而言之，这种初步的经验表明，这种新的导线可为大多数患者提供通过CS进行安全可靠的永久性LV起搏，并且可以单独使用或与右心室起搏结合使用以实现双心室同步。

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