Brugada pattern electrocardiogram associated with supratherapeutic phenytoin levels and the risk of sudden death.

Al-Aloul B; Adabag AS; Houghland MA; Tholakanahalli V

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Brugada pattern electrocardiogram associated with supratherapeutic phenytoin levels and the risk of sudden death.

机译：Brugada模式心电图与超治疗苯妥英水平和猝死风险有关。

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The emergence of Brugada pattern on electrocardiogram in response to class IA or IC antiarrhythmic agents is widely utilized to diagnose concealed Brugada syndrome and recognized as a risk factor for sudden death. Phenytoin, a class IB antiarrhythmic agent, has not been reported to induce Brugada pattern. We report a patient who presented with Brugada electrocardiogram at supratherapeutic phenytoin level. Considering that patients with syncope may falsely be labeled to have seizures and some epilepsy patients are at increased risk of sudden death, all patients with supratherapeutic phenytoin level should be evaluated with an electrocardiogram for emergence of Brugada pattern.

机译：对IA或IC类抗心律不齐药物的反应，心电图上出现Brugada模式已被广泛用于诊断隐蔽的Brugada综合征，并被认为是猝死的危险因素。苯妥英钠是一种IB类抗心律不齐药，尚未报道可诱导Brugada模式。我们报告了一名患者，在治疗性苯妥英钠水平上接受Brugada心电图检查。考虑到晕厥患者可能被错误地标记为癫痫发作，并且某些癫痫患者的猝死风险更高，因此应对所有具有治疗上苯妥英水平的患者进行心电图检查，以评估是否出现Brugada模式。

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《PACE: Pacing and clinical electrophysiology》 |2007年第5期|共3页
作者
Al-Aloul B; Adabag AS; Houghland MA; Tholakanahalli V;
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正文语种 eng
中图分类诊断学;
关键词
Pattern; Electrocardiogram; Phenytoin level; Death; Sudden; 猝死;

机译：模式;心电图;苯妥英水平;死亡;突然;猝死;

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1. Brugada pattern electrocardiogram associated with supratherapeutic phenytoin levels and the risk of sudden death. [J] . Al-Aloul B, Adabag AS, Houghland MA, PACE: Pacing and clinical electrophysiology . 2007,第5期

机译：Brugada模式心电图与超治疗苯妥英水平和猝死风险有关。
2. Relatively benign clinical course in asymptomatic patients with brugada-type electrocardiogram without family history of sudden death. [J] . Takenaka S, Kusano KF, Hisamatsu K, Journal of cardiovascular electrophysiology . 2001,第1期

机译：无猝死家族史的无症状布鲁加达型心电图患者的临床过程相对较好。
3. Epilepsy, Brugada syndrome and the risk of sudden unexpected death. [J] . Fauchier L, Babuty D, Cosnay P Journal of neurology . 2000,第8期

机译：癫痫，Brugada综合征和突然意外死亡的风险。
4. CLINICAL RELEVANCE OF PILSICAINIDE CHALLENGETEST FOR RISK STRATIFICATION OF SUDDEN CARDIACDEATH IN PATIENTS WITH BRUGADA TYPE ECG [C] . SHINGO SASAKI, ATSUSHIIWASA, TAKUMI HIGUMA, International Congress on Electrocardiology . 2005

机译：Brugada型心电图患者突然心肌危险性挑战的临床相关性
5. Arrhythmia Risk Predictors in Populations with High versus Low Risk for Sudden Death. [D] . Nazarian, Saman. 2012

机译：高或低猝死风险人群中的心律失常风险预测指标。
6. The electrocardiogram in apparently healthy men and the risk of sudden death. [O] . S W Rabkin, F L Mathewson, R B Tate 1982

机译：显然健康的男人的心电图和猝死风险。
7. The electrocardiogram in apparently healthy men and the risk of sudden death. [O] . Rabkin, S W, Mathewson, F L, Tate, R B 1982

机译：显然健康的男人的心电图和猝死风险。
8. Assessment on Implantable Defibrillators and the Evidence for Primary Prevention of Sudden Cardiac Death. Technology Assessment Report. [R] . Uhlig, K., Balk, E. M., Earley, A., 2013

机译：植入式除颤器的评估和一级预防突发性心脏病死亡的证据。技术评估报告。

Brugada pattern electrocardiogram associated with supratherapeutic phenytoin levels and the risk of sudden death.

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