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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Effect of ischemic stroke on the dynamic beat-to-beat QT-RR relationship.
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Effect of ischemic stroke on the dynamic beat-to-beat QT-RR relationship.

机译：缺血性卒中对动态心律比QT-RR关系的影响。

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摘要

The ECGs of 26 patients following ischemic stroke and 18 control patients with various orthopedic problems, all without primary heart disease, were examined to characterize the dynamic behavior of uncorrected QT interval in relation to changing RR interval during physiotherapy effort. ECG waveforms were analyzed to extract beat-to-beat QT and RR intervals. Based on performing multiple cross-correlations, the relationship between the RR and QT intervals was calculated using the following general formula QTi = c RRib-1. Linear regression was performed on the logarithms of QT and RR measurements to estimate the constant (a = log c) and the slope (b) values, reflecting the dynamic change of QT during physiotherapy effort. Having these two values, the dynamic QT extrapolated to a heart period of 1 second (QTcd) was calculated. It was found that the mean slope (b) of the linear regression line in the ischemic stroke group was significantly lower than in the control group (0.26 +/- 0.08 vs 0.33 +/- 0.08, P < 0.02), and the constant (a) was significantly higher (1.83 +/- 0.21 for the ischemic stroke vs 1.61 +/- 0.23 for the controls, P < 0.002). No significant difference was found in QTcd values between the two groups (386 +/- 27 ms for the ischemic stroke vs 392 +/- 25 ms for the controls, P > 0.05). In conclusion, hemispheric brain infarction seems to result in alteration in the autonomic activity during exercise manifesting itself as distorted dynamic behavior of the QT interval.
机译：检查了26名缺血性卒中患者的ECG和18名患有各种骨科疾病的对照患者（均无原发性心脏病），以表征在理疗过程中未校正QT间隔与RR间隔改变相关的动态行为。分析ECG波形以提取逐搏QT和RR间隔。基于执行多个互相关，使用以下通式QTi = c RRib-1计算RR和QT间隔之间的关系。对QT和RR测量的对数执行线性回归以估计常数（a = log c）和斜率（b）值，反映了理疗过程中QT的动态变化。有了这两个值，就可以计算出推断到1秒心脏周期（QTcd）的动态QT。发现缺血性卒中组线性回归线的平均斜率（b）显着低于对照组（0.26 +/- 0.08对0.33 +/- 0.08，P <0.02），并且常数（ a）明显更高（缺血性卒中为1.83 +/- 0.21，对照组为1.61 +/- 0.23，P <0.002）。两组之间的QTcd值无显着差异（缺血性卒中为386 +/- 27 ms，对照组为392 +/- 25 ms，P> 0.05）。总之，半球性脑梗塞似乎导致运动过程中自主神经活动的改变，表现为QT间隔的动态行为扭曲。

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