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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Intra- and interatrial conduction delay: implications for cardiac pacing.
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Intra- and interatrial conduction delay: implications for cardiac pacing.

机译:房内和房间传导延迟:对心脏起搏的影响。

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摘要

Atrial conduction disorders are frequent in elderly subjects and/or those with structural heart diseases, mainly mitral valve disease, hyperthrophic cardiomyopathies, and hypertension. The resultant electrophysiological and electromechanical abnormalities are associated with a higher risk of paroxysmal or persistent atrial tachyarrhythmias, either atrial fibrillation, typical or atypical flutter or other forms of atrial tachycardias. Such an association is not fortuitous because intra- and interatrial conduction abnormalities delays disrupt (spatial and temporal dispersion) electrical activation, thus promoting the initiation and perpetuation of reentrant circuits. Preventive therapeutic interventions induce variable, sometimes paradoxical effects as with the proarrhythmic effect of class I antiarrhythmic drugs. Similarly, atrial pacing may promote proarrhythmias or an antiarrhythmic effect according to the pacing site(s) and mode. Multisite atrial pacing was conceived to correct, as much as possible, abnormal activation induced by spontaneous intra- or interatrial conduction disorders or by single site atrial pacing, which are situations responsible for commonly refractory arrhythmias. Atrial electrical resynchronization can also be used to correct mechanical abnormalities like left heart AV dyssynchrony resulting from intraatrial conduction delays.
机译:心房传导异常在老年受试者和/或患有结构性心脏病(主要是二尖瓣疾病,肥大性心肌病和高血压)的患者中很常见。导致的电生理和机电异常与阵发性或持续性房性快速性心律失常的较高风险有关,房颤是典型的或非典型性扑动或其他形式的心动过速。这种关联不是偶然的,因为心内和心房传导异常会延迟干扰(空间和时间分散)电激活,从而促进折返电路的启动和持续。预防性治疗干预会产生不同的,有时甚至是矛盾的作用,就像I类抗心律不齐药物的心律失常作用一样。同样,根据起搏部位和方式,心房起搏可促进心律失常或抗心律失常作用。多部位心房起搏被认为是尽可能纠正由自发性房内或房间传导障碍或单部位心房起搏引起的异常激活,这是导致难治性心律失常的原因。心房电同步还可用于纠正由于房内传导延迟导致的机械异常,如左心房室不同步。

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