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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Effect of a pacing mode preserving spontaneous AV conduction on ventricular pacing burden and atrial arrhythmias
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Effect of a pacing mode preserving spontaneous AV conduction on ventricular pacing burden and atrial arrhythmias

机译：起搏模式保持自发性房室传导对心室起搏负担和心律失常的影响

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Background: Using dual-chamber pacemakers with new algorithms: Manage Ventricular Pacing (MVP?), minimizes unnecessary ventricular pacing (VP). This function operates in AAI/R mode with backup VP during AV block. Aim: The aim of "Generation MVP" study was to assess the VP burden and atrial arrhythmias (AA) burden according to indication of pacing and MVP? function programming of AdaptaDR implantable pacemaker (Medtronic Inc., Minneapolis, MN, USA). Methods: The multicenter observational "Generation MVP" study included 220 patients aged 75.9 ± 11 years (men = 52%) implanted for sinus node dysfunction (SND; n = 115) or atrio-ventricular block (AVB; n = 105). Programming MVP function has been left to the physician's discretion. Percentage of VP and AA burden (percentage of time spent in AA) stored in memories were assessed at 2 and 10 months. Results: 220 patients were followed at 2 months (174 MVP [On], 46 MVP [off]) and at 10 months (165 MVP [On], 55 MVP [off]). Median percentage of VP is significantly lower when MVP is programmed [On] versus [off] at 2 and 10 months follow-up for SND and AVB indications of pacing (P < 0.001). Finally, programming MVP function is performed at middle term (10 months) for 84% of patients with SND and 65% of patients with AVB: median percentage of VP is as low as 0.6% for patients with SND and 12% for patients with AVB versus 95% for SND and 99% for AVB when MVP function is programmed [off](P < 0.001). Median AA burden was significantly lower when MVP function was programmed [On] versus [off] at 2 months (8.7% vs 28%; P < 0.001) and 10 months (1% vs 22%; P < 0.001). Conclusion: In this study programming MVP function decreases percentage of VP at 2 and 10 months for patients paced for SND or AVB. Moreover median AA burden is reduced when MVP function was programmed [On] vs [off] at two follow-ups. (PACE 2012; 1-6)
机译：背景：将双室起搏器与新算法配合使用：管理心室起搏（MVP），可最大程度地减少不必要的心室起搏（VP）。在AV块期间，此功能在带有备份VP的AAI / R模式下运行。目的：“产生MVP”研究的目的是根据起搏和MVP的指征评估VP负担和房性心律失常（AA）负担？ AdaptaDR植入式起搏器的功能编程（美国明尼苏达州明尼阿波利斯的美敦力公司）。方法：多中心观察性“ Generation MVP”研究包括220例75.9±11岁（男性= 52％）的因窦房结功能不全（SND; n = 115）或房室传导阻滞（AVB; n = 105）植入的患者。编程MVP功能由医生决定。在2和10个月时评估存储在内存中的VP和AA负担百分比（在AA中所花费的时间百分比）。结果：220例患者在2个月（174 MVP [开启]，46 MVP [关闭]）和10个月（165 MVP [开启]，55 MVP [关闭]）得到随访。在SND和AVB起搏的2个月和10个月随访中，将MVP编程为[开]与[关]时，VP的中位数百分比显着降低（P <0.001）。最后，在84％的SND患者和65％的AVB患者的中期（10个月）执行编程MVP功能：SND患者的VP中位数低至0.6％，AVB患者的12％相比[S]的95％（SND）和99％（AVB）（当MVP功能被编程为[off]（P <0.001）时）。在2个月（8.7％vs 28％; P <0.001）和10个月（1％vs 22％; P <0.001）时，将MVP功能编程为[开]与[关]时，AA的中位数显着降低。结论：在本研究中，对于SND或AVB分级的患者，编程MVP功能可在2个月和10个月时降低VP百分比。此外，在两次随访中将MVP功能编程为[开]与[关]时，中位AA负担减少了。 （PACE 2012; 1-6）

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