New chiral borohydride based reducing agent: Asymmetric reduction of 9-anthryl trifluoromethyl ketone and other carbonyl compounds

Maiti DK.; Bhattacharya PK.

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New chiral borohydride based reducing agent: Asymmetric reduction of 9-anthryl trifluoromethyl ketone and other carbonyl compounds

机译：新的基于手性硼氢化物的还原剂：9-蒽三氟甲基酮和其他羰基化合物的不对称还原

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(S)-(+)-2-(alpha-Hydroxybenzyl)benzimidazole (1) and (S)-(-)-2-benzimidazole-1-ethanol (2) were synthesised and converted to chiral borohydrides which reduced prochiral ketones to the corresponding chiral alcohols in high yields (80 to 100%, e.e. 42 to 95%). This is the first report of sodium borohydride modified by 1,2-amino alcohol. [References: 56]

机译：合成了（S）-（+）-2-（α-羟基苄基）苯并咪唑（1）和（S）-（-）-2-苯并咪唑-1-乙醇（2）并转化为手性硼氢化物，该化合物将前手性酮还原为相应的手性醇收率很高（80％至100％，ee 42％至95％）。这是1,2-氨基醇改性硼氢化钠的首次报道。 [参考：56]

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《Synthetic Communications》 |1998年第1期|共10页
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Maiti DK.; Bhattacharya PK.;
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中图分类有机化学;
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1. New chiral borohydride based reducing agent: Asymmetric reduction of 9-anthryl trifluoromethyl ketone and other carbonyl compounds [J] . Maiti DK., Bhattacharya PK. Synthetic Communications . 1998,第1期

机译：新的基于手性硼氢化物的还原剂：9-蒽三氟甲基酮和其他羰基化合物的不对称还原
2. Direct reductive amination of aldehydes and ketones with 2,4-ionene-based borohydride exchange resin as a novel polymer-supported reducing agent [J] . Tajbakhsh M, Lakouraj MM, Mahalli MS Synthetic Communications . 2008,第12期

机译：用2,4-紫罗烯基硼氢化物交换树脂作为新型的聚合物负载型还原剂对醛和酮进行直接还原胺化
3. Direct Reductive Amination of Aldehydes and Ketones with 2,4-Ionene-Based Borohydride Exchange Resin as a Novel Polymer-Supported Reducing Agent [J] . Mahmood Tajbakhsh, Moslem Mansour Lakouraj, Majid Shabani Mahalli Synthetic Communications . 2008,第10a12期

机译：以2,4-氧化烯基的硼氢化物交换树脂作为新型的聚合物支持的还原剂对醛和酮进行直接还原胺化
4. Enantioselective Cyanation of Ketones and α,β-Unsaturated Carbonyl Compounds Catalyzed by Chiral Lithium Phosphoryl Phenoxide [C] . Katsuya Yamakawa, Manabu Hatano, Kazuaki Ishihara 日本化学会春季年会講演予稿集 . 2018

机译：由手性锂磷酰苯氧铵催化的酮和α，β-不饱和羰基化合物的对映选择性的氰化物
5. Part I. Asymmetric synthesis of bicyclic analogues of risedronate as molecular probes of the mechanism of action of bisphosphonate antiosteoporotic drugs and potentially more efficacious antiosteoporotic agents. Part II. Facile preparation and functionalization of chiral stabilized ylides from common chiral auxiliaries using the Bestmann ylide and their use in Wittig reactions. Part III. Asymmetric organocatalysis: 1. An investigation of alpha-hydroxylation of aldehydes; 2. Synthesis of a novel camphor-based alpha-aminotetrazole organocatalyst. [D] . Song, Xinyi. 2007

机译：第一部分：利塞膦酸盐双环类似物的不对称合成，作为双膦酸盐类抗骨质疏松药和潜在更有效的抗骨质疏松药作用机理的分子探针。第二部分使用Bestmann内酯从常见手性助剂轻松制备和官能化手性稳定化的叶基及其在Wittig反应中的用途。第三部分不对称有机催化：1.醛的α-羟基化研究； 2.合成新的基于樟脑的α-氨基四唑有机催化剂。
6. Novel anti-Prelog stereospecific carbonyl reductases from Candida parapsilosis for asymmetric reduction of prochiral ketones [O] . Yao Nie, Rong Xiao, Yan Xu, -1

机译：从近平滑念珠菌新型抗普雷洛格立体特异性羰基还原酶为不对称还原前手性酮的
7. ASYMMETRIC REDUCTION OF PROCHIRAL KETONES WITH A CHIRAL REDUCING AGENT PREPARED FROM STANNOUS CHLORIDE, CHIRAL DIAMINE AS A LIGAND, AND DIISOBUTYLALUMINUM HYDRIDE [O] . Takeshi Oriyama, Teruaki Mukaiyama 1984

机译：具有由氯化锡，手性胺作为配体制备的手性还原剂的前三丙酮的不对称还原，以及二异丁基铝氢化物
8. Addition Compounds of Alkali Metal Hydrides. 29. Preparation and Properties of Chiral Dialkylmonoalkoxy-borohydrides. A New Class of Asymmetric Reducing Agents [R] . Brown, H. C., Park, W. S., Cho, B. T. 1986

机译：碱金属氢化物的加成化合物。 29.手性二烷基单烷氧基硼氢化物的制备和性质。一类新的不对称还原剂

New chiral borohydride based reducing agent: Asymmetric reduction of 9-anthryl trifluoromethyl ketone and other carbonyl compounds

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