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Effects of an advanced sleep schedule and morning short wavelength light exposure on circadian phase in young adults with late sleep schedules.

机译:提前睡眠计划和早晨短波长光暴露对具有较晚睡眠计划的年轻人的昼夜节律的影响。

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OBJECTIVE: We examined the effects of an advanced sleep/wake schedule and morning short wavelength (blue) light in 25 adults (mean age+/-SD=21.8+/-3 years; 13 women) with late sleep schedules and subclinical features of delayed sleep phase disorder (DSPD). METHODS: After a baseline week, participants kept individualized, fixed, advanced 7.5-h sleep schedules for 6days. Participants were randomly assigned to groups to receive "blue" (470nm, approximately 225lux, n=12) or "dim" (<1lux, n=13) light for 1h after waking each day. Head-worn Daysimeters schedule compliance. Salivary dim light melatonin onset (DLMO), self-reported sleep, and mood were examined with 2x2 ANOVA. RESULTS: After 6days, both groups showed significant circadian phase advances, but morning blue light was not associated with larger phase shifts than dim-light exposure. The average DLMO advances (mean+/-SD) were 1.5+/-1.1h in the dim light group and 1.4+/-0.7h in the blue light group. CONCLUSIONS: Adherence to a fixed advanced sleep/wake schedule resulted in significant circadian phase shifts in young adults with subclinical DSPD with or without morning blue light exposure. Light/dark exposures associated with fixed early sleep schedules are sufficient to advance circadian phase in young adults.
机译:目的:我们研究了提前睡眠/唤醒时间表和早晨短波长(蓝色)光对25位成年人(平均年龄+/- SD = 21.8 +/- 3岁; 13位女性)的影响,这些行为具有延迟的睡眠时间表和延迟的亚临床特征睡眠阶段障碍(DSPD)。方法:在基准周之后,参与者保持个性化,固定的,先进的7.5小时睡眠计划,持续6天。每天醒来后,将参与者随机分配到各组中,以接受1h的“蓝色”(470nm,大约225lux,n = 12)或“昏暗的”(<1lux,n = 13)光。戴在头戴的日程计可确保符合规定。用2x2方差分析检测唾液暗淡褪黑激素发作(DLMO),自我报告的睡眠和情绪。结果:6天后,两组均显示出明显的昼夜节律相移,但早晨的蓝光与昏暗的光线照射相比没有更大的相移。暗光组的平均DLMO前进量(平均值+/- SD)为1.5 +/- 1.1h,蓝光组为1.4 +/- 0.7h。结论:坚持固定的高级睡眠/唤醒时间表会导致患有亚临床DSPD的年轻成年人在有或没有早晨蓝光照射的情况下发生明显的昼夜节律相移。与固定的早期睡眠时间表相关的光/暗接触足以使年轻成年人的昼夜节律阶段发展。

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