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首页> 外文期刊>Sleep medicine >Age-related changes in periodic leg movements during sleep in patients with restless legs syndrome.
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Age-related changes in periodic leg movements during sleep in patients with restless legs syndrome.

机译：腿不安定综合征患者睡眠期间周期性腿部运动与年龄有关的变化。

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OBJECTIVE: The aim of this study was to evaluate and statistically describe the age-related changes in leg movements (LMs) during sleep in a large group of subjects with restless legs syndrome (RLS). SUBJECTS AND METHODS: One hundred eight untreated patients affected by idiopathic RLS were included in this study (mean age 52.0years, min 7.5, max 83.2years). The time structure of their polysomnographically recorded LMs was analyzed using an approach particularly appropriate for assessing their quantity, periodicity, and distribution during the night. RESULTS: Periodic LMs during sleep (PLMS) increased in number gradually in the age groups. Their typical interval was approximately 24-28s before the age of 55years but at approximately 14-16s after the age of 65years. PLMS index reached a plateau at 15-25years of age and remained stable up to 65years; after this age, it showed an important increase. Periodicity index (PI) increased progressively up to the age of 35years and then remained stable up to the age of 85years. No correlation was found between PLMS index and PI. The number of PLMS per hour of sleep declined through the night in subjects aged 15-75years; after this age, PLMS tended to be equally distributed across the entire night. CONCLUSIONS: The use of three main parameters derived from the analysis of leg motor activity during sleep in RLS patients (PLMS index, PI and PLMS time distribution) is capable of providing us with important information about the age-related changes of PLMS in this condition, which can be used in the evaluation of the sleep motor patterns in these subjects.
机译：目的：本研究的目的是评估和统计描述一大群患有躁动性腿综合征（RLS）的受试者在睡眠过程中与腿相关的年龄变化（LMs）。受试者和方法：这项研究包括了108名未经治疗的特发性RLS患者（平均年龄52.0岁，最低7.5岁，最高83.2岁）。使用特别适合评估夜间数量，周期性和分布的方法分析了多导睡眠图记录的LM的时间结构。结果：年龄段的周期性睡眠中LM（PLMS）数量逐渐增加。他们的典型间隔大约是55岁之前的24-28s，但在65岁之后大约14-16s。 PLMS指数在15至25岁时达到稳定水平，并在65岁时保持稳定;在这个年龄之后，它显示出重要的增长。周期性指数（PI）在35岁之前逐渐增加，然后在85岁之前保持稳定。在PLMS指数和PI之间未发现相关性。在15-75岁的受试者中，夜间每小时PLMS的数量下降了;在这个年龄之后，PLMS倾向于在整个晚上均匀分布。结论：使用RLS患者睡眠期间腿部运动活动分析得出的三个主要参数（PLMS指数，PI和PLMS时间分布）能够为我们提供有关这种情况下与年龄相关的PLMS变化的重要信息。 ，可用于评估这些对象的睡眠运动模式。

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