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首页> 外文期刊>Pancreatology: official journal of the International Association of Pancreatology (IAP) ... [et al.] >Clinical, emotional and social factors associated with quality of life in chronic pancreatitis.
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Clinical, emotional and social factors associated with quality of life in chronic pancreatitis.

机译：与慢性胰腺炎生活质量相关的临床，情感和社会因素。

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BACKGROUND: In chronic pancreatitis (CP), a debilitating, progressive and incurable disease, patients' wellbeing is considerably impaired, but the different factors affecting quality of life (QoL), have not been identified yet. METHODS: 69 patients with CP were evaluated (M/F 55/14; mean age 46.6 +/- 10.05 years). Different degrees of pancreatic damage were defined using the Cambridge classification; pain intensity and frequency were assessed using pain index. QoL was measured using EORTC QLQ-C30 and the PAN26 questionnaire. Although developed for pancreatic cancer, the C30/PAN26 has been validated for chronic pancreatitis. RESULTS: Digestive symptoms, financial difficulties, fear of future health and general pain scales showed considerable effects of CP on QoL. We observed significant negative correlation between mean QoL scores and pain index in almost all domains (p < 0.001, p < 0.05). Pain intensity affects QoL scales more often than pain frequency. BMI correlated positively with QoL in global health status, altered bowel habits, body image and satisfaction with health care domains (p < 0.01, p < 0.05). CONCLUSION: Pain index, BMI, Cambridge classification and disease duration are the most important factors adversely affecting QoL in CP. Measurement of QoL is essential in the disease management and improves the knowledge of psychosocial functioning of these patients. and IAP.
机译：背景：在慢性胰腺炎（CP）中，这是一种令人衰弱，进行性和不治之症，患者的健康受到很大损害，但尚未发现影响生活质量（QoL）的不同因素。方法：对69名CP患者进行了评估（男/女55/14;平均年龄46.6 +/- 10.05岁）。使用剑桥分类法定义了不同程度的胰腺损害。使用疼痛指数评估疼痛强度和频率。使用EORTC QLQ-C30和PAN26问卷测量QoL。尽管开发用于胰腺癌，但C30 / PAN26已被证实可用于慢性胰腺炎。结果：消化系统症状，经济困难，对未来健康的恐惧和一般疼痛程度表明CP对生活质量的影响很大。我们观察到几乎所有领域的平均QoL评分与疼痛指数之间均存在显着的负相关性（p <0.001，p <0.05）。疼痛强度比疼痛频率更频繁地影响生活质量量表。 BMI与全球健康状况，改变的排便习惯，身体形象以及对医疗保健领域的满意度方面的QoL呈正相关（p <0.01，p <0.05）。结论：疼痛指数，BMI，Cambridge分类和病程是影响CP患者QoL的最重要因素。 QoL的测量在疾病管理中至关重要，并提高了这些患者的心理社会功能知识。和IAP。

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