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首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >A research synthesis of therapeutic interventions for whiplash-associated disorder: part 1 - overview and summary.
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A research synthesis of therapeutic interventions for whiplash-associated disorder: part 1 - overview and summary.

机译:鞭打相关疾病的治疗干预研究综述:第1部分-概述和总结。

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摘要

Whiplash-associated disorder (WAD) represents a significant public health problem, resulting in a substantial socioeconomic burden throughout the industrialized world, wherever costs are documented. While many treatments have been advocated for patients with WAD, scientific evidence of their effectiveness is often lacking. A systematic review was conducted to evaluate the strength of evidence supporting various WAD therapies. Multiple databases (including Web of Science, EMBASE and PubMed) were searched to identify all studies published from January 1980 through March 2009 that evaluated the effectiveness of any clearly defined treatment for acute (less than two weeks), subacute (two to 12 weeks) or chronic (longer than 12 weeks) WAD. The present article, the first in a five-part series, provides an overview of the review methodology as well as a summary and discussion of the review's main findings. Eighty-three studies met the inclusion criteria, 40 of which were randomized controlled trials. The majority of studies (n=47) evaluated treatments initiated in the chronic stage of the disorder, while 23 evaluated treatments for acute WAD and 13 assessed therapies for subacute WAD. Exercise and mobilization programs for acute and chronic WAD had the strongest supporting evidence, although many questions remain regarding the relative effectiveness of various protocols. At present, there is insufficient evidence to support any treatment for subacute WAD. For patients with chronic WAD who do not respond to conventional treatments, it appears that radiofrequency neurotomy may be the most effective treatment option. The present review found a relatively weak but growing research base on which one could make recommendations for patients at any stage of the WAD continuum. Further research is needed to determine which treatments are most effective at reducing the disabling symptoms associated with WAD.
机译:鞭打相关疾病(WAD)代表着重大的公共卫生问题,无论记录在何处,都会给整个工业化世界带来巨大的社会经济负担。虽然有人主张对WAD患者采取多种治疗方法,但通常缺乏其有效性的科学证据。进行了系统的评估,以评估支持各种WAD疗法的证据的强度。搜索多个数据库(包括Web of Science,EMBASE和PubMed),以鉴定1980年1月至2009年3月发表的所有研究,这些研究评估了任何明确定义的治疗急性(少于两周),亚急性(两到12周)的有效性。或慢性(超过12周)WAD。本文是由五部分组成的系列文章的第一篇,它概述了审查方法,并对审查的主要发现进行了总结和讨论。八十三项研究符合纳入标准,其中四十项为随机对照试验。大多数研究(n = 47)评估了该疾病慢性阶段开始的治疗,而23项评估了急性WAD的治疗和13项评估了亚急性WAD的治疗。急性和慢性WAD的运动和动员计划具有最有力的支持证据,尽管各种方案的相对有效性仍然存在许多疑问。目前,没有足够的证据支持对亚急性WAD的任何治疗。对于对常规治疗无反应的慢性WAD患者,看来射频神经切开术可能是最有效的治疗选择。本综述发现了一个相对薄弱但发展中的研究基础,可以为WAD连续体任何阶段的患者提供建议。需要进一步的研究来确定哪种疗法最有效地减轻与WAD相关的致残症状。

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