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首页> 外文期刊>Pain medicine : >The efficacy of transforaminal injection of steroids for the treatment of lumbar radicular pain.
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The efficacy of transforaminal injection of steroids for the treatment of lumbar radicular pain.

机译：经椎间孔注射类固醇治疗腰部神经根疼痛的功效。

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BACKGROUND: Transforaminal injection of steroids is used to treat lumbar radicular pain. Not known is whether the route of injection or the agent injected is significant. STUDY DESIGN: A prospective, randomized study compared the outcomes of transforaminal injection of steroid and local anesthetic, local anesthetic alone, or normal saline, and intramuscular injection of steroid or normal saline. Patients and outcome evaluators were blinded as to agent administered. METHODS: The primary outcome measure was the proportion of patients who achieved complete relief of pain, or at least 50% relief, at 1 month after treatment. Secondary outcome measures were function, disability, patient-specified functional outcomes, use of other health care, and duration of relief beyond 1 month. RESULTS: A significantly greater proportion of patients treated with transforaminal injection of steroid (54%) achieved relief of pain than did patients treated with transforaminal injection of local anesthetic (7%) or transforaminal injection of saline (19%), intramuscular steroids (21%), or intramuscular saline (13%). Relief of pain was corroborated by significant improvements in function and disability, and reductions in use of other health care. Outcomes were equivalent for patients with acute or chronic radicular pain. Over time, the number of patients who maintained relief diminished. Only some maintained relief beyond 12 months. The proportions of patients doing so were not significantly different statistically between groups. DISCUSSION: Transforaminal injection of steroids is effective only in a proportion of patients. Its superiority over other injections is obscured when group data are compared but emerges when categorical outcomes are calculated. Over time, the proportion of patients with maintained responses diminishes.
机译：背景：经椎间孔注射类固醇用于治疗腰部神经根痛。尚不清楚注射途径或注射剂是否重要。研究设计：一项前瞻性随机研究比较了经椎间孔注射类固醇和局麻药，单独局麻药或生理盐水，以及肌内注射类固醇或生理盐水的结果。患者和结果评估者对所用药物不知情。方法：主要结局指标是治疗后1个月完全缓解疼痛或至少缓解50％的患者比例。次要结局指标包括功能，残疾，患者指定的功能结局，使用其他医疗保健以及缓解期超过1个月。结果：经椎间孔注射类固醇治疗的患者（54％）比经椎间孔注射局部麻醉药（7％）或经椎间孔注射生理盐水（19％），肌内类固醇（21％）的患者缓解疼痛的比例明显更高。 ％）或肌注生理盐水（13％）。功能和残疾的显着改善以及减少其他医疗保健的使用证实了疼痛的缓解。结果对于患有急性或慢性根性疼痛的患者是等效的。随着时间的流逝，维持缓解的患者数量减少了。只有一些人在12个月后维持救济。两组之间的患者比例在统计学上无显着差异。讨论：经椎间孔类固醇注射仅对部分患者有效。当比较组数据时，其优于其他注射剂的优势被发现，但当计算出分类结果时，其优势显现出来。随着时间的流逝，维持反应的患者比例逐渐减少。

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