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首页> 外文期刊>Parasitology >Evidence of human neurocysticercosis in Slovenia.
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Evidence of human neurocysticercosis in Slovenia.

机译:斯洛文尼亚人类神经囊虫病的证据。

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摘要

To assess the prevalence of Taenia solium cysticercosis in patients with neurological disorders in Slovenia, serum/cerebrospinal fluid (CSF) samples from 348 suspected patients were collected between the beginning of January 2001 and the end of December 2012 and analysed serologically for the presence of anti-T. solium IgG antibodies. Of 20 patients whose samples tested positive or equivocal by enzyme-linked immunosorbent assay (ELISA), samples of 7 patients were confirmed positive by Western blot (WB). The overall seroprevalence rate of T. solium infection in patients with neurological disorders included in the study was 2.0%. Serological results of positive patients corresponded to clinical and/or imaging findings concerning their brain cysts. Based on their personal data, it was ascertained that neurocysticercosis (NCC) positive patients had immigrated or came to Slovenia from the former Yugoslav republics. Since the disease is believed not to be endemic in Slovenia we assume that all of the NCC-positive patients had acquired the infection before immigration to Slovenia or visiting or being visited by their relatives infected with an adult T. solium parasite. The present results represent the first insight into the prevalence of NCC in patients with neurological disorders in Slovenia.
机译:为了评估斯洛文尼亚神经系统疾病患者patients虫囊虫的患病率,在2001年1月开始至2012年12月底之间收集了348例疑似患者的血清/脑脊液(CSF)样本,并进行了血清学分析-T IgG抗体。在通过酶联免疫吸附测定(ELISA)检测出阳性或不明确的20例患者中,通过Western blot(WB)证实了7例患者的阳性。该研究中包括的神经系统疾病患者的总T. solium血清阳性率为2.0%。阳性患者的血清学结果与有关其脑囊肿的临床和/或影像学发现相对应。根据他们的个人数据,可以确定神经囊尾osis病(NCC)阳性患者已从前南斯拉夫各共和国移民或来到斯洛文尼亚。由于认为该病在斯洛文尼亚不是地方病,因此我们假设所有NCC阳性患者在移民到斯洛文尼亚或探亲或感染其成年疟原虫的亲戚之前就已感染。目前的结果代表了对斯洛文尼亚神经系统疾病患者中NCC患病率的首次见解。

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