...
首页> 外文期刊>Parasitology >Morphological characterization of Cryptosporidium parvum life-cycle stages in an in vitro model system.
【24h】

Morphological characterization of Cryptosporidium parvum life-cycle stages in an in vitro model system.

机译:体外模型系统中隐孢子虫生命周期阶段的形态学表征。

获取原文
获取原文并翻译 | 示例
           

摘要

Cryptosporidium parvum is a zoonotic protozoan parasite that mainly affects the ileum of humans and livestock, with the potential to cause severe enteric disease. We describe the complete life cycle of C. parvum in an in vitro system. Infected cultures of the human ileocecal epithelial cell line (HCT-8) were observed over time using electron microscopy. Additional data are presented on the morphology, development and behavioural characteristics of the different life-cycle stages as well as determining their time of occurrence after inoculation. Numerous stages of C. parvum and their behaviour have been visualized and morphologically characterized for the first time using scanning electron microscopy. Further, parasite-host interactions and the effect of C. parvum on host cells were also visualized. An improved understanding of the parasite's biology, proliferation and interactions with host cells will aid in the development of treatments for the disease.
机译:小隐孢子虫是一种人畜共患的原生动物寄生虫,主要影响人和牲畜的回肠,有可能引起严重的肠病。我们描述了体外系统中小球藻的完整生命周期。随着时间的流逝,使用电子显微镜观察到了人类回盲肠上皮细胞系(HCT-8)的感染培养物。还提供了有关不同生命周期阶段的形态,发育和行为特征以及确定接种后它们发生时间的其他数据。使用扫描电子显微镜首次观察到了小菜蛾的多个阶段及其行为,并对其形态进行了表征。此外,还可以观察到寄生虫与宿主的相互作用以及小隐孢子虫对宿主细胞的作用。对寄生虫的生物学,增殖以及与宿主细胞相互作用的进一步了解将有助于开发该疾病的治疗方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号