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Thermodynamics of trematode infectivity

机译:吸虫感染的热力学

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Temperature is an important factor influencing the biology of organisms and is intrinsically linked to climate change. The establishment of trematodes in target hosts is potentially susceptible to temperature changes effecting parasite infectivity or host susceptibility, and therefore in order to develop predictive frameworks of host-parasite dynamics under climate change large-scale analyses are required. The present study analyses the thermodynamics of the infectivity of larval trematodes including miracidia, cercariae and metacercariae from experimental data contained in the scientific literature using the Arrhenius critical incremental energy of activation (E*), an accurate measure of temperature-driven reaction rates. For miracidia and cercariae, infectivity increases as the temperature rises reaching a plateau over optimal thermal ranges before declining at higher temperatures. In contrast, metacercarial infectivity is at its greatest at low temperatures, declining with increasing temperature.
机译:温度是影响生物体生物学的重要因素,并且与气候变化具有内在联系。在目标宿主中建立吸虫可能容易受到温度变化的影响,从而影响寄生虫的传染性或宿主的敏感性,因此,为了建立气候变化下宿主-寄生虫动态的预测框架,需要进行大规模分析。本研究使用Arrhenius临界激活增量能(E *)从科学文献中包含的实验数据中分析了包括miraturia,尾c和尾尾aria在内的幼虫吸虫的感染热力学,该温度是温度驱动的反应速率的精确度量。对于水acid和尾c,随着温度升高,在最佳热范围内达到平稳,传染性增加,然后在较高温度下下降。相反,在低温下,meta骨的感染力最大,随着温度的升高而下降。

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