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首页> 外文期刊>Biomaterials >Preparation and in vitro bioactivity of hydroxyapatite/solgel glass biphasic material.
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Preparation and in vitro bioactivity of hydroxyapatite/solgel glass biphasic material.

机译：羟基磷灰石/溶胶凝胶玻璃两相材料的制备及其体外生物活性。

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摘要

Hydroxyapatite/solgel glass biphasic material has been obtained in order to improve the bioactivity of the hydroxyapatite (OHAp). A mixture of stoichiometric OHAp and the precursor gel of a solgel glass, with nominal composition in mol% CaO-26, SiO2-70, P205-4, has been prepared. The amounts of components used have been selected to obtain a final relationship for OHAp/solgel glass of 60/40 on heating. Two different thermal treatments have been used: (i) 700 degrees C, temperature of solgel glass stabilisation and (ii) 1000 degrees C, lower temperature of hydroxyapatite sintering. The bioactivity of the resulting materials has been examined in vitro by immersion in simulated body fluid at 37 degrees C. The results obtained show that both materials are bioactive. The apatite-like layer grown is greater for the new materials than for the OHAp and the solgel glass themselves.
机译：为了提高羟基磷灰石（OHAp）的生物活性，已经获得了羟基磷灰石/溶胶凝胶玻璃两相材料。制备了化学计量的OHAp和溶胶凝胶玻璃的前体凝胶的混合物，其标称组成为CaO-26，SiO2-70，P205-4摩尔％。选择所使用的组分的量以获得加热时OHAp /溶胶凝胶玻璃的最终关系为60/40。已经使用了两种不同的热处理：（​​i）700摄氏度，溶胶凝胶玻璃稳定化温度，和（ii）1000摄氏度，较低温度的羟磷灰石烧结。通过在37℃下浸入模拟体液中体外检查了所得材料的生物活性。获得的结果表明两种材料均具有生物活性。对于新材料而言，生长的磷灰石样层要比OHAp和溶胶凝胶玻璃本身要大。

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