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首页> 外文期刊>Parkinsonism & related disorders >Traditional neuropsychological correlates and reliability of the Automated Neuropsychological Assessment Metrics-4 battery for Parkinson's disease
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Traditional neuropsychological correlates and reliability of the Automated Neuropsychological Assessment Metrics-4 battery for Parkinson's disease

机译：传统神经心理学相关性和帕金森氏病自动神经心理评估指标4电池的可靠性

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Background: The Automated Neuropsychological Assessment Metrics Battery-4 for PD offers the promise of a computerized approach to cognitive assessment. Methods: To assess its utility, the ANAM4-PD was administered to 72 PD patients and 24 controls along with a traditional battery. Reliability was assessed by retesting 26 patients. Results: The Cognitive Efficiency Score (CES; a global score) exhibited high reliability (r = 0.86). Constituent variables exhibited lower reliability. The CES correlated strongly with the traditional battery global score, but displayed weaker relationships to UPDRS scores than the traditional score. Multivariate analysis of variance revealed a significant difference between the patient and control groups in ANAM4-PD performance, with three ANAM4-PD tests, Math, Tower, and Pursuit Tracking, displaying sizeable differences. In discriminant analyses these variables were as effective as the total ANAM4-PD in classifying cases designated as impaired based on traditional variables. Principal components analyses uncovered fewer factors in the ANAM4-PD relative to the traditional battery. ANAM4-PD variables correlated at higher levels with traditional motor and processing speed variables than with untimed executive, intellectual or memory variables. Conclusions: The ANAM4-PD displays high global reliability, but variable subtest reliability. The battery assesses a narrower range of cognitive functions than traditional tests, and discriminates between patients and controls less effectively. Three ANAM4-PD tests, Pursuit Tracking, Math, and Tower performed as well as the total ANAM4-PD in classifying patients as cognitively impaired. These findings could guide the refinement of the ANAM4-PD as an efficient method of screening for mild to moderate cognitive deficits in PD patients.
机译：背景：PD的自动神经心理评估指标Battery-4有望以计算机化的方式进行认知评估。方法：为了评估其实用性，将ANAM4-PD与传统电池一起施用于72例PD患者和24名对照。通过重新测试26位患者来评估可靠性。结果：认知效率评分（CES;全球评分）显示出很高的可靠性（r = 0.86）。组成变量表现出较低的可靠性。 CES与传统电池总体评分高度相关，但与UPDRS评分的关系却比传统评分弱。方差的多变量分析显示，在患者和对照组之间，ANAM4-PD的性能存在显着差异，通过进行三个数学，塔式和追踪追踪的ANAM4-PD测试，显示出相当大的差异。在判别分析中，这些变量在根据传统变量对指定为受损的病例进行分类时与总ANAM4-PD一样有效。主成分分析发现与传统电池相比，ANAM4-PD中的因​​素更少。与非定时执行，智能或记忆变量相比，ANAM4-PD变量与传统电机和处理速度变量的相关程度更高。结论：ANAM4-PD显示出较高的整体可靠性，但子测试可靠性却可变。与传统测试相比，该电池评估的认知功能范围更窄，并且在区分患者和对照方面的效果较差。在将患者归类为认知障碍患者方面，进行了三个ANAM4-PD测试，追踪追踪，数学和Tower测试以及总的ANAM4-PD测试。这些发现可以指导ANAM4-PD的改进，作为筛选PD患者中轻度至中度认知缺陷的有效方法。

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