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首页> 外文期刊>Swiss medical weekly: official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology >Adverse effects and adherence to treatment of rifampicin 4 months vs isoniazid 6 months for latent tuberculosis A retrospective analysis
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Adverse effects and adherence to treatment of rifampicin 4 months vs isoniazid 6 months for latent tuberculosis A retrospective analysis

机译:潜伏性结核病利福平4个月vs异烟肼6个月的不良反应和依从性回顾性分析

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摘要

To compare completion rates and rates of treatment interruption because of side effects and/or hepato-toxicity between subjects treated for latent tuberculosis infection (LTBI) by isoniazid (TNH) for 6 months and subjects treated with rifampicin (RIF) for 4 months.A 4-month RIF treatment was associated with significantly less interruption of treatment because of hepatotoxicity and higher completion rates compared to a 6-month INH regimen.
机译:为了比较异烟肼(TNH)治疗潜伏性结核感染(LTBI)的受试者6个月和利福平(RIF)治疗的受试者4个月的完成率和因副作用和/或肝毒性引起的治疗中断率。与6个月的INH方案相比,由于肝毒性和较高的完成率,4个月的RIF治疗与治疗中断显着相关。

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