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Non-invasive prenatal screening for trisomy 21: What women want and are willing to pay

机译：21三体性的无创产前筛查：女性想要并愿意付出的代价

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Objective: To investigate the attitude among pregnant women regarding non-invasive prenatal testing (NIPT) for detecting trisomy 21 (T21) and to quantify their willingness to pay for NIPT. Methods: A questionnaire was administered to pregnant women who received counselling for first-trimester screening (FTS) in two hospitals and nine midwife practices in the Netherlands. Results: A total of 147 women completed the questionnaire, yielding a response rate of 43%. If NIPT for detecting T21 were available, 81% stated they would choose to have this test, and 57% of women who elected not to undergo FTS in their current pregnancy would perform NIPT if available. Willingness to pay for NIPT was correlated with age and income, but not education level. The price that participants were willing to pay for NIPT was similar to the current price for FTS. Conclusion: The pregnant women in our study had a positive attitude regarding NIPT for T21, and more than half of the women who rejected prenatal screening would receive NIPT if available. Practice implications: Due to the elimination of iatrogenic miscarriage, caregivers should be aware that informed decision-making can change with respect to prenatal screening with the introduction of NIPT.
机译：目的：探讨孕妇对无创性产前检查（NIPT）检测21三体性疾病（T21）的态度，并量化其支付NIPT的意愿。方法：对在荷兰两家医院和九名助产士诊所接受孕早期筛查（FTS）咨询的孕妇进行问卷调查。结果：共有147名妇女填写了问卷，答复率为43％。如果可以使用NIPT来检测T21，则81％的人表示他们会选择进行此检查，而在当前怀孕时选择不接受FTS的女性中，有57％会进行NIPT。支付NIPT的意愿与年龄和收入相关，但与受教育程度无关。参与者愿意为NIPT支付的价格与当前FTS的价格相似。结论：我们研究中的孕妇对NIPT对于T21持积极态度，如果可以，拒绝产前筛查的孕妇中有一半以上会接受NIPT。实际意义：由于消除了医源性流产，护理人员应意识到引入NIPT可以在产前筛查方面做出明智的决策。

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