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首页> 外文期刊>Pediatric cardiology >Long-term follow-up of children and adolescents diagnosed with hypertrophic cardiomyopathy: risk factors for adverse arrhythmic events.
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Long-term follow-up of children and adolescents diagnosed with hypertrophic cardiomyopathy: risk factors for adverse arrhythmic events.

机译:诊断为肥厚型心肌病的儿童和青少年的长期随访:不良心律失常事件的危险因素。

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摘要

Our aim was to identify prognostic factors for an arrhythmic event (AE) in children with hypertrophic cardiomyopathy (HCM) without a previous AE. One hundred thirty-one nonconsecutive patients (/= 20 mm, 19% (95% CI: 6-31%) when age >/= 13 years and ST >/= 20 mm were combined together, and 23% (95% CI: 3-39%) when PVS and ST >/= 20 mm were combined together. Of the various risk factors that were considered in our pediatric HCM cohort, ST and inducible VT were the most significant univariate predictors of risk for an AE. More traditional risk factors identified in older patients (family history of SD, VT on Holter, and exercise-induced hypotension) were not predictive of an AE in patients age under 21 years.
机译:我们的目的是确定没有先前AE的肥厚型心肌病(HCM)儿童的心律失常事件(AE)的预后因素。美国国立卫生研究院临床中心从1980年至2001年对113例非连续性HCM患者( / = 20 mm,则AE的5年事件发生率为15%(95%CI:5-23%),当年龄> / = 13岁时为19%(95%CI:6-31%)。和ST> / = 20 mm合并在一起,当PVS和ST> / = 20 mm合并在一起时为23%(95%CI:3-39%)。在我们的儿科HCM队列中考虑的各种风险因素中,ST和可诱发性VT是AE风险的最重要单变量预测因子。在老年患者中发现的更多传统危险因素(SD家族史,动态心电图室速以及运动引起的低血压)不能预测21岁以下患者发生AE。

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