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Head injury depth as an indicator of causes and mechanisms.

机译:头部受伤深度可作为原因和机制的指标。

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OBJECTIVE: The goal was to measure differences in the causes, mechanisms, acute clinical presentations, injuries, and outcomes of children <36 months of age with varying "greatest depths" of acute cranial injury. METHODS: Children <36 months of age who were hospitalized with acute head trauma were recruited at multiple sites. Clinical and imaging data were collected, and caregivers underwent scripted interviews. Neurodevelopmental evaluations were completed 6 months after injury. Head trauma causes were categorized independently, and subject groups with varying greatest depths of injury were compared. RESULTS: Fifty-four subjects were enrolled at 9 sites. Twenty-seven subjects underwent follow-up neurodevelopmental assessments 6 months after injury. Greatest depth of visible injury was categorized as scalp, skull, or epidural for 20 subjects, subarachnoid or subdural for 13, cortical for 10, and subcortical for 11. Compared with subjects with more-superficial injuries, subjects with subcortical injuries more frequently had been abused (odds ratio [OR]: 35.6; P < .001), more frequently demonstrated inertial injuries (P < .001), more frequently manifested acute respiratory (OR: 43.9; P < .001) and/or circulatory (OR: 60.0; P < .001) compromise, acute encephalopathy (OR: 28.5; P = .003), prolonged impairments of consciousness (OR: 8.4; P = .002), interhemispheric subdural hemorrhage (OR: 10.1; P = .019), and bilateral brain hypoxia, ischemia, or swelling (OR: 241.6; P < .001), and had lower Mental Developmental Index (P = .006) and Gross Motor Quotient (P < .001) scores 6 months after injury. CONCLUSION: For children <3 years of age, head injury depth is a useful indicator of injury causes and mechanisms.
机译:目的:目的是测量36岁以下,急性颅脑损伤“最大深度”不同的儿童的病因,机制,急性临床表现,损伤和结局的差异。方法:从多个地点招募了因急性头部创伤而住院的<36个月的儿童。收集了临床和影像数据,并且照护者接受了脚本访谈。损伤后6个月完成神经发育评估。对头部外伤的原因进行了独立分类,并比较了最大损伤深度不同的受试者组。结果:在9个地点招募了54名受试者。 27名受试者在受伤后6个月接受了神经发育评估。可见损伤的最大深度分类为:头皮,颅骨或硬膜外20例,蛛网膜下或硬膜下13例,皮层10例,皮层下11例。与浅表伤相比,皮层下损伤更常见滥用(赔率[OR]:35.6; P <.001),惯常性损伤(P <.001),急性呼吸道疾病(OR:43.9; P <.001)和/或循环系统(OR: 60.0; P <.001)妥协,急性脑病(OR:28.5; P = .003),长期意识障碍(OR:8.4; P = .002),半球间硬膜下出血(OR:10.1; P = .019) ,以及双侧脑缺氧,局部缺血或肿胀(OR:241.6; P <.001),并且在受伤后6个月的心理发展指数(P = .006)和总运动智商(P <.001)得分较低。结论:对于3岁以下的儿童,头部受伤深度是受伤原因和机制的有用指标。

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