首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Unintentional child poisonings through ingestion of conventional and novel tobacco products.
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Unintentional child poisonings through ingestion of conventional and novel tobacco products.

机译:摄入常规和新型烟草制品会意外造成儿童中毒。

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OBJECTIVE: This study examines child poisonings resulting from ingestion of tobacco products throughout the nation and assesses the potential toxicity of novel smokeless tobacco products, which are of concern with their discreet form, candy-like appearance, and added flavorings that may be attractive to young children. METHODS: Data representing all single-substance, accidental poisonings resulting from ingestion of tobacco products by children <6 years of age, reported to poison control centers, were examined. Age association with ingestion of smokeless tobacco versus other tobacco products was tested through logistic regression. Total nicotine content, pH, and un-ionized nicotine level were determined, and the latter was compared with values for moist snuff and cigarettes. RESULTS: A total of 13,705 tobacco product ingestion cases were reported, >70% of which involved infants <1 year of age. Smokeless tobacco products were the second most common tobacco products ingested by children, after cigarettes, and represented an increasing proportion of tobacco ingestions with each year of age from 0 to 5 years (odds ratio: 1.94 [95% confidence interval: 1.86-2.03]). A novel, dissolvable, smokeless tobacco product with discreet form, candy-like appearance, and added flavorings was found to contain an average of 0.83 mg of nicotine per pellet, with an average pH of 7.9, which resulted in an average of 42% of the nicotine in the un-ionized form. CONCLUSION: In light of the novelty and potential harm of dissolvable nicotine products, public health authorities are advised to study these products to determine the appropriate regulatory approach.
机译:目的:这项研究检查了全国范围内因摄入烟草制品而引起的儿童中毒,并评估了新型无烟烟草制品的潜在毒性,这与它们谨慎的形式,类似糖果的外观以及可能对年轻人有吸引力的增香剂有关。孩子们。方法:检查了报告给毒物控制中心的,代表由<6岁的儿童摄入烟草制品导致的所有单一物质,意外中毒的数据。通过逻辑回归检验了与无烟烟草与其他烟草产品相比的年龄相关性。确定总尼古丁含量,pH和未电离的尼古丁含量,并将后者与湿鼻烟和香烟的值进行比较。结果:总共报告了13705例烟草制品摄入病例,其中> 70%涉及1岁以下的婴儿。无烟烟草制品是儿童摄入的第二大烟草制品,仅次于香烟,并且占从0岁到5岁的每一年烟草摄入量的比例不断增加(赔率:1.94 [95%置信区间:1.86-2.03] )。发现一种新的,可溶的,无烟的烟草产品,具有谨慎的形式,类似糖果的外观和添加的调味剂,每粒颗粒平均含有0.83 mg尼古丁,平均pH值为7.9,平均结果为42%非电离形式的尼古丁。结论:鉴于可溶尼古丁产品的新颖性和潜在危害,建议公共卫生当局对这些产品进行研究,以确定适当的监管方法。

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