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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Prevalence of spina bifida among children and adolescents in 10 regions in the United States.
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Prevalence of spina bifida among children and adolescents in 10 regions in the United States.

机译：美国10个地区的儿童和青少年中脊柱裂的患病率。

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摘要

OBJECTIVE: The goal was to estimate the number of children and adolescents, 0 to 19 years of age, living with spina bifida (SB) in the United States. METHODS: A retrospective study was conducted by using population-based, birth defect surveillance data from 10 US regions, with vital status ascertainment. Birth defect surveillance data were obtained from Arkansas, Georgia (5 central counties of metropolitan Atlanta), California (11 counties), Colorado, Iowa, New York (New York City excluded), North Carolina, Oklahoma, Texas, and Utah. We estimated the numbers of children 0 to 19 years of age who were living with SB in the 10 US regions in 2002, according to age group, race/ethnicity, and gender, and examined a long-term trend in the prevalence of SB among children 0 to 11 years of age in 1991-2002. RESULTS: The overall prevalence of SB among children and adolescents 0 to 19 years of age in the study regions was 3.1 cases per 10,000 in 2002. The prevalence of SB among children was lower among male and non-Hispanic black children. CONCLUSIONS: The prevalence estimates of SB among children and adolescents varied according to region, race/ethnicity, and gender, which suggests possible variations in prevalence at birth and/or inequities in survival rates. Additional studies are warranted to elucidate the reasons for these variations and to derive prevalence estimates of SB among adults.
机译：目的：目的是估计美国生活在脊柱裂中的儿童和青少年人数（0至19岁）。方法：使用来自美国10个地区的以人口为基础的出生缺陷监测数据进行回顾性研究，确定生命状态。出生缺陷监测数据来自阿肯色州，佐治亚州（亚特兰大都会区的5个中心县），加利福尼亚州（11个县），科罗拉多州，爱荷华州，纽约州（不包括纽约市），北卡罗来纳州，俄克拉荷马州，德克萨斯州和犹他州。根据年龄组，种族/民族和性别，我们估计了2002年美国10个地区的SB患0至19岁儿童的数量，并调查了SB患病率的长期趋势1991-2002年为0到11岁的儿童。结果：2002年研究区0至19岁儿童和青少年中SB的总体患病率为每10,000例3.1例。男性和非西班牙裔黑人儿童中儿童SB的患病率较低。结论：根据地区，种族/民族和性别，儿童和青少年中SB的患病率估计值有所不同，这表明出生时患病率和/或生存率不平等可能存在差异。有必要进行额外的研究来阐明这些差异的原因，并得出成年人中SB的患病率估计值。

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