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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Growth hormone: health considerations beyond height gain.
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Growth hormone: health considerations beyond height gain.

机译：生长激素：超出身高的健康考虑因素。

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摘要

The therapeutic benefit of growth hormone (GH) therapy in improving height in short children is widely recognized; however, GH therapy is associated with other metabolic actions that may be of benefit in these children. Beneficial effects of GH on body composition have been documented in several different patient populations as well as improvements in lipid profile. Marked augmentation of bone mineral density also seems evident in many pediatric populations. Some of these benefits may require continued therapy past the acquisition of adult height. With long-term therapy of any kind, the adverse consequences of treatment should also be considered. Fortunately, long-term GH treatment seems to be safe and well-tolerated. This review describes the long-term metabolic effects of GH treatment in the pediatric population and considers how these may benefit children who are treated with GH.
机译：生长激素（GH）疗法在改善矮小的儿童身高方面的治疗优势已广为人知;然而，GH疗法与其他代谢作用有关，可能对这些儿童有益。 GH对人体成分的有益作用已在数个不同的患者人群中得到了证明，并且脂质水平得到改善。在许多儿科人群中，骨矿物质密度的明显增加也很明显。其中一些好处可能需要在获得成人身高后继续进行治疗。对于任何种类的长期治疗，都应考虑治疗的不良后果。幸运的是，长期GH治疗似乎是安全且耐受性良好的。这篇综述描述了GH治疗在儿科人群中的长期代谢作用，并考虑了这些可能如何使接受GH治疗的儿童受益。

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