Concurrent treatment of steroid-related mood and psychotic symptoms with risperidone.

Ularntinon S; Tzuang D; Dahl G; Shaw RJ

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Concurrent treatment of steroid-related mood and psychotic symptoms with risperidone.

机译：利培酮同时治疗类固醇相关的情绪和精神病症状。

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Corticosteroid treatment is an important therapeutic modality for many pediatric medical conditions including acute lymphoblastic leukemia. However, steroid-induced behavioral and mood abnormalities are common and potentially disabling adverse effects that have been widely reported in the pediatric literature. From this case series, we report the efficacy of risperidone in 3 children with acute lymphoblastic leukemia who developed steroid-related mood and psychotic symptoms during treatment with prednisone and dexamethasone. Risperidone is an effective short-term pharmacologic agent for controlling steroid-related psychiatric adverse effects when cessation or dose reduction of steroid therapy is not an option.

机译：皮质类固醇治疗是许多儿科疾病（包括急性淋巴细胞白血病）的重要治疗方式。但是，类固醇诱导的行为和情绪异常很普遍，并且可能使不良反应失效，这已在儿科文献中广泛报道。从该病例系列中，我们报告了利培酮对3例在泼尼松和地塞米松治疗期间出现类固醇相关的情绪和精神病症状的急性淋巴细胞白血病儿童的疗效。当不能选择停止或减少类固醇治疗剂量时，利培酮是一种有效的短期药物，可控制类固醇相关的精神疾病的不良反应。

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《Pediatrics: Official Publication of the American Academy of Pediatrics》 |2010年第5期|共5页
作者
Ularntinon S; Tzuang D; Dahl G; Shaw RJ;
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正文语种 eng
中图分类儿科学;
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1. Concurrent treatment of steroid-related mood and psychotic symptoms with risperidone. [J] . Ularntinon S, Tzuang D, Dahl G, Pediatrics: Official Publication of the American Academy of Pediatrics . 2010,第5期

机译：利培酮同时治疗类固醇相关的情绪和精神病症状。
2. Mood-congruent and mood-incongruent psychotic symptoms in major depression: The role of severity and personality [J] . TonnaM., DePanfilisC., MarchesiC. Journal of affective disorders . 2012,第2a3期

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3. Psychotic Symptoms are Selectively Associated with Mood Symptom Severity and Worse Outcome in Pediatric Bipolar Disorder [J] . Bachman Peter, Merranko John, Tello Itziar Baltasar, Early intervention in psychiatry . 2018,第S1期

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Concurrent treatment of steroid-related mood and psychotic symptoms with risperidone.

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