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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >'Remarkable improvement': sulfa drugs and pediatric meningococcal meningitis, 1937-1949.
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'Remarkable improvement': sulfa drugs and pediatric meningococcal meningitis, 1937-1949.

机译:“显着改善”:磺胺类药物和小儿脑膜炎球菌性脑膜炎,1937-1949年。

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摘要

Lauded as one of the greatest developments of 20th-century medicine, the "wonder drug" penicillin reshaped the treatment of infectious diseases and altered patterns of mortality. As a result, the breakthrough that preceded penicillin-the development of the sulfonamides-is often overlooked.Using records from Sydenham Hospital, a municipal communicable disease institution in Baltimore, Maryland, in which nearly 75% of patients were children, we show the transformative role that sulfa drugs played in pediatric practice through a case study of me-ningococcal meningitis.
机译:作为20世纪医学最伟大的发展之一,“神奇药”青霉素重塑了传染病的治疗方法,并改变了死亡率。因此,在青霉素之前的突破-磺酰胺的开发-通常被忽略了。利用马里兰州巴尔的摩市传染病机构Sydenham医院的记录,其中近75%的患者是儿童,我们证明了这种转化性通过脑膜炎球菌性脑膜炎的案例研究,磺胺类药物在儿科实践中发挥的作用。

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