Cognition and Brain Structure Following Early Childhood Surgery With Anesthesia

Backeljauw Barynia; Holland Scott K.; Altaye Mekibib; Loepke Andreas W.

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Cognition and Brain Structure Following Early Childhood Surgery With Anesthesia

机译：幼儿麻醉手术后的认知和脑结构

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BACKGROUND: Anesthetics induce widespread cell death, permanent neuronal deletion, and neurocognitive impairment in immature animals, raising substantial concerns about similar effects occurring in young children. Epidemiologic studies have been unable to sufficiently address this concern, in part due to reliance on group-administered achievement tests, inability to assess brain structure, and limited control for confounders.

机译：背景：麻醉药会引起未成熟动物的广泛细胞死亡，永久性神经元缺失和神经认知障碍，引起人们对年幼儿童发生类似作用的担忧。流行病学研究未能充分解决这一问题，部分原因是依赖于团体管理的成就测试，无法评估大脑结构以及对混杂因素的控制有限。

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《Pediatrics: Official Publication of the American Academy of Pediatrics》 |2015年第1期|共12页
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Backeljauw Barynia; Holland Scott K.; Altaye Mekibib; Loepke Andreas W.;
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正文语种 eng
中图分类儿科学;
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1. Cognition and Brain Structure Following Early Childhood Surgery With Anesthesia [J] . Backeljauw Barynia, Holland Scott K., Altaye Mekibib, Pediatrics: Official Publication of the American Academy of Pediatrics . 2015,第1期

机译：幼儿麻醉手术后的认知和脑结构
2. Shoulder Surgery in the Beach Chair Position Is Associated with Diminished Cerebral Autoregulation but No Differences in Postoperative Cognition or Brain Injury Biomarker Levels Compared with Supine Positioning: The Anesthesia Patient Safety Foundation Beach Chair Study [J] . Laflam Andrew, Joshi Brijen, Brady Kenneth, Anesthesia and Analgesia: Journal of the International Anesthesia Research Society . 2015,第1期

机译：沙滩椅位置的肩部手术与脑自动调节减弱有关，但与仰卧位相比，术后认知或脑损伤生物标志物水平无差异：麻醉患者安全基金会沙滩椅研究
3. SU115 Interaction effects of childhood adversity and glutamatergic polygenic risk score on brain structure and cognition in schizophrenia (vol 29, pg S1268, 2019) [J] . Saini Suriati Mohamed, Mancuso Sam, Liu Chenxing, European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology . 2019,第10期

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4. Brain structures recognition using MER signals and medical images - application to brain deep stimulation surgery [C] . Orozco Alvaro A., Garcia Hernan F., Vargas Hernan D., International Work Conference on Bio-inspired Intelligence . 2014

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5. The effects of physical activity on the brain and cognition during childhood. [D] . Chaddock, Laura. 2012

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6. Cognition and Brain Structure Following Early Childhood Surgery With Anesthesia [O] . Barynia Backeljauw, Scott K. Holland, Mekibib Altaye, -1

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7. What’s new in Emergencies, Trauma and Shock? Anesthesia, surgery and postoperative cognition [O] . Ramaiah, Ramesh 2011

机译：紧急情况，创伤和休克有什么新变化？麻醉，手术和术后认知

Cognition and Brain Structure Following Early Childhood Surgery With Anesthesia

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