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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Growth characteristics of infantile hemangiomas: implications for management.
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Growth characteristics of infantile hemangiomas: implications for management.

机译：婴儿血管瘤的生长特征：对管理的影响。

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OBJECTIVES: Infantile hemangiomas often are inapparent at birth and have a period of rapid growth during early infancy followed by gradual involution. More precise information on growth could help predict short-term outcomes and make decisions about when referral or intervention, if needed, should be initiated. The objective of this study was to describe growth characteristics of infantile hemangioma and compare growth with infantile hemangioma referral patterns. METHODS: A prospective cohort study involving 7 tertiary care pediatric dermatology practices was conducted. Growth data were available for a subset of 526 infantile hemangiomas in 433 patients from a cohort study of 1096 children. Inclusion criteria were age younger than 18 months at time of enrollment and presence of at least 1 infantile hemangioma. Growth stage and rate were compared with clinical characteristics and timing of referrals. RESULTS: Eighty percent of hemangioma size was reached during the early proliferative stage at a mean age of 3 months. Differences in growth between hemangioma subtypes included that deep hemangiomas tend to grow later and longer than superficial hemangiomas and that segmental hemangiomas tended to exhibit more continued growth after 3 months of age. The mean age of first visit was 5 months. Factors that predicted need for follow-up included ongoing proliferation, larger size, deep component, and segmental and indeterminate morphologic subtypes. CONCLUSIONS: Most infantile hemangioma growth occurs before 5 months, yet 5 months was also the mean age at first visit to a specialist. Recognition of growth characteristics and factors that predict the need for follow-up could help aid in clinical decision-making. The first few weeks to months of life are a critical time in hemangioma growth. Infants with hemangiomas need close observation during this period, and those who need specialty care should be referred and seen as early as possible within this critical growth period.
机译：目的：小儿血管瘤通常在出生时是不明显的，并且在婴儿早期有一段快速的成长期，然后逐渐消退。关于生长的更精确信息可以帮助预测短期结果，并在需要时决定何时开始转诊或干预。这项研究的目的是描述婴儿血管瘤的生长特征，并将其与婴儿血管瘤转诊模式进行比较。方法：进行了一项前瞻性队列研究，涉及7种三级护理小儿皮肤病学实践。一项来自1096名儿童的队列研究获得了433名患者中526名婴儿血管瘤的子集的生长数据。入选标准为入组时年龄小于18个月且存在至少1例婴儿血管瘤。将生长阶段和生长速度与转诊的临床特征和时间进行比较。结果：在增生早期，平均年龄为3个月，达到了血管瘤大小的80％。血管瘤亚型之间的生长差异包括深层血管瘤倾向于比浅表血管瘤生长更晚，更长，而节段性血管瘤在3个月大以后往往表现出更多的持续生长。初诊的平均年龄为5个月。预测需要随访的因素包括持续的增殖，更大的大小，较深的成分以及节段性和不确定的形态亚型。结论：大多数婴儿血管瘤的生长发生在5个月之前，但5个月也是初诊时的平均年龄。识别生长特征和预测需要随访的因素有助于临床决策。生命的最初几周至几个月是血管瘤生长的关键时期。在此期间，患有血管瘤的婴儿需要密切观察，而需要特殊护理的婴儿应在这个关键的生长期内尽早转诊并接受检查。

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