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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Recognition and management of iatrogenically induced opioid dependence and withdrawal in children
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Recognition and management of iatrogenically induced opioid dependence and withdrawal in children

机译：儿童医源性阿片类药物依赖和戒断的识别和处理

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摘要

Opioids are often prescribed to children for pain relief related to procedures, acute injuries, and chronic conditions. Round-the-clock dosing of opioids can produce opioid dependence within 5 days. According to a 2001 Consensus Paper from the American Academy of Pain Medicine, American Pain Society, and American Society of Addiction Medicine, dependence is defined as "a state of adaptation that is manifested by a drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, and/or administration of an antagonist." Although the experience of many children undergoing iatrogenically induced withdrawal may be mild or goes unreported, there is currently no guidance for recognition or management of withdrawal for this population. Guidance on this subject is available only for adults and primarily for adults with substance use disorders. The guideline will summarize existing literature and provide readers with information currently not available in any single source specific for this vulnerable pediatric population.
机译：阿片类药物通常开给儿童以减轻与手术，急性损伤和慢性病有关的疼痛。全天服用阿片类药物可在5天内产生阿片类药物依赖性。根据2001年美国疼痛医学科学院，美国疼痛学会和美国成瘾医学学会的共识文件，依赖性被定义为“一种适应性状态，其表现为可能由突然产生的药物类别特异性戒断综合症停止，快速降低剂量，降低药物的血药水平和/或施用拮抗剂。”尽管许多儿童因医源性戒断而经历的经历可能是轻度的或没有报道，但目前尚无该人群识别或管理戒断的指南。此主题的指南仅适用于成年人，主要适用于患有药物滥用疾病的成年人。该指南将总结现有文献，并为读者提供当前针对该弱势儿科人群的任何单一来源目前都无法获得的信息。

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