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Comparative Effectiveness Research Through a Collaborative Electronic Reporting Consortium

机译：通过协作电子报告联盟进行的比较有效性研究

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摘要

The United States lacks a system to use routinely collected electronic health record (EHR) clinical data to conduct comparative effectiveness research (CER) on pediatric drug therapeutics and other child health topics. This Special Article describes the creation and details of a network of EHR networks devised to use clinical data in EHRs for conducting CER, led by the American Academy of Pediatrics Pediatric Research in Office Settings (PROS). To achieve this goal, PROS has linked data from its own EHR-based "ePROS" network with data from independent practices and health systems across the United States. Beginning with 4 of proof-of-concept retrospective CER studies on psychotropic and asthma medication use and side effects with a planned full-scale prospective CER study on treatment of pediatric hypertension, the Comparative Effectiveness Research Through Collaborative Electronic Reporting (CER2) collaborators are developing a platform to advance the methodology of pediatric pharmacoepidemiology. CER2 will provide a resource for future CER studies in pediatric drug therapeutics and other child health topics. This article outlines the vision for and present composition of this network, governance, and challenges and opportunities for using the network to advance child health and health care. The goal of this network is to engage child health researchers from around the United States in participating in collaborative research using the CER2 database.
机译：美国缺乏使用常规收集的电子健康记录（EHR）临床数据进行儿科药物治疗和其他儿童健康主题的比较有效性研究（CER）的系统。这篇特殊文章描述了由美国儿科学会儿科研究中心（PROS）领导的EHR网络的创建和详细信息，该网络旨在使用EHR中的临床数据进行CER。为了实现这一目标，PROS已将其基于EHR的“ ePROS”网络中的数据与来自美国各地独立实践和卫生系统的数据相链接。从4项有关精神和哮喘药物使用和副作用的概念性CER回顾性CER研究开始，以及计划中的用于治疗小儿高血压的全面前瞻性CER研究，通过协作电子报告（CER2）协作者的比较有效性研究正在进行中一个促进儿科药物流行病学方法学的平台。 CER2将为将来在儿科药物治疗和其他儿童健康主题中进行CER研究提供资源。本文概述了该网络的构想和现状，治理，使用该网络促进儿童健康和卫生保健的挑战和机遇。该网络的目标是吸引来自美国各地的儿童健康研究人员参与使用CER2数据库进行的合作研究。

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