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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Treatment for retinopathy of prematurity in Denmark in a ten-year period (1996 2005): is the incidence increasing?
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Treatment for retinopathy of prematurity in Denmark in a ten-year period (1996 2005): is the incidence increasing?

机译：丹麦在十年内治疗早产儿视网膜病变（1996年至2005年）：发病率在增加吗？

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摘要

OBJECTIVE: The objective of this study was to analyze the population incidence of retinopathy of prematurity treatment in Denmark in the 10-year period from 1996 to 2005. METHODS: Patient charts of infants treated for retinopathy of prematurity and the national birth registry provide information about neonatal parameters. These parameters, along with birth in the latter half of the period (2001-2005), were analyzed as risk factors for retinopathy of prematurity. The national registry for blind and visually impaired children was accessed to obtain information about visual impairment attributable to retinopathy of prematurity in both treated and untreated infants. RESULTS: The study population consisted of 5467 Danish preterm infants born in 1996 to 2005, with a gestational age of < 32 weeks, who survived for > or = 5 postnatal weeks; 2616 were born in 1996 to 2000, and 2851 were born in 2001 to 2005. The incidence of treated retinopathy of prematurity cases increased significantly from 1.3% in 1996 to 2000 to 3.5% in 2001 to 2005. Significant risk factors for retinopathy of prematurity treatment were low gestational age, small for gestational age, male gender, and multiple birth. Other, yet unknown factors contributed to the increased incidence in the latter half of the period. Of the study population, 0.6% were registered as visually impaired because of retinopathy of prematurity within 2 years after birth (early-detected visual impairment). The incidences were not significantly different between 1996 to 2000 and 2001 to 2005. Of all of the early-detected, visually impaired children, 16% had not been treated for retinopathy of prematurity and were considered screening failures. CONCLUSIONS: The incidence of retinopathy of prematurity treatment in Denmark has more than doubled during the past half-decade. This increase could not be fully explained by increased survival rates for the infants or by changes in the investigated neonatal risk factors.
机译：目的：本研究的目的是分析丹麦从1996年至2005年的10年中早产儿视网膜病变的发生率。方法：接受过早产儿视网膜病变治疗的婴儿病历表和国家出生登记簿可提供有关新生儿参数。分析了这些参数以及该期后半段（2001-2005年）的出生情况，将其作为早产儿视网膜病变的危险因素。访问了国家盲人和视觉障碍儿童注册表，以获取有关治疗和未治疗婴儿早产儿视网膜病变可归因的视觉障碍的信息。结果：研究人群包括5467名丹麦早产儿，出生于1996年至2005年，胎龄＜32周，存活≥5周。 1996年至2000年有2616例出生，2001年至2001年有2851例。早产儿视网膜病变的治疗率从1996年的1.3％显着增加到2001年至2005年的3.5％。早产儿视网膜病变的重要危险因素胎龄低，胎龄小，男性，多胎。其他但未知的因素导致了该期后半段发病率的增加。在研究人群中，有0.6％的人由于出生后2年内早产儿视网膜病变（早期发现的视觉障碍）而被注册为视力障碍。在1996年至2000年以及2001年至2005年之间，发病率没有显着差异。在所有早期发现的视力障碍儿童中，有16％的儿童未接受过早产儿视网膜病变的治疗，被认为是筛查失败。结论：在过去的五年中，丹麦早产儿视网膜病变的发生率增加了一倍以上。不能通过婴儿存活率的增加或所调查的新生儿危险因素的变化来完全解释这种增加。

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