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首页> 外文期刊>Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies >Early exchange and pheresis therapies in critical pertussis'
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Early exchange and pheresis therapies in critical pertussis'

机译：危重性百日咳的早期交换和截肢疗法

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摘要

This issue of Pediatric Critical Care Medicine includes a case report by Dr. Martinez and colleagues (1) on the use of exchange transfusion in a case of critical pertussis occurring in an 8-wk-old infant girl. To date, most reports of series of fatal Bordetella pertussis show a female prevalence in mortality (2, 3); although this may be confounded where immunization practices differ by gender. As well, the prevalence of pertussis critical illness in unimmunized, very young infants as compared with other age groups is well known (4, 5). Although the physiologic nature and etiology of these findings is beginning to emerge in ongoing studies as well as recent reports (6-8), it is encouraging to consider this report of the successful use of exchange transfusion to modify the course of this life-threatening and persistent problem. Critical pertussis illness is beginning to be described as "fulminant" and "malignant," as differentiated from the outpatient coughing illness (9, 10).
机译：本期《儿科重症监护医学》包括Martinez博士及其同事的病例报告（1），该研究报道了在8周大的女婴发生严重百日咳的情况下使用交换输血的情况。迄今为止，大多数关于致命性百日咳博德特氏菌系列的报告都表明女性死亡率较高（2、3）;而女性百日咳死亡率却很高。尽管在免疫实践因性别而异的情况下可能会感到困惑。同样，与其他年龄组相比，未免疫的非常年轻的婴儿中百日咳危重病的患病率也是众所周知的（4、5）。尽管这些发现的生理性质和病因学在正在进行的研究以及最近的报道中开始出现（6-8），但是令人鼓舞的是，考虑成功使用交换输血来改变这一危及生命的过程的报告和持续存在的问题。严重的百日咳病已开始被描述为“暴发性”和“恶性”，与门诊咳嗽病有所区别（9，10）。

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