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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Dysfunctional elimination syndrome: is it related to urinary tract infection or vesicoureteral reflux diagnosed early in life?
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Dysfunctional elimination syndrome: is it related to urinary tract infection or vesicoureteral reflux diagnosed early in life?

机译：功能障碍消除综合征：与生命早期诊断出的尿路感染或膀胱输尿管反流有关吗？

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OBJECTIVE: It has been suggested that urinary tract infections (UTIs) early in life predispose to dysfunctional elimination syndrome (DES). This study evaluated the relationship between early UTI, vesicoureteral reflux (VUR), and DES by comparing two cohorts of school-aged children. METHODS: The UTI cohort (n = 123) included children previously enrolled in a prospective treatment trial conducted between 1992 and 1997. All were diagnosed with a febrile UTI before 2 years of age. The comparison cohort (n = 125) included children who were evaluated for fever in the emergency department between 1992 and 1997, whose urine culture was negative. Dysfunctional elimination symptoms were compared in the two cohorts by having families complete a revised version of the Dysfunctional Voiding Scoring System. RESULTS: Completed questionnaires were received from 248 children. There were no significant differences in selected demographic or clinical characteristics between the two cohorts. DES was present in 22% and 21% of children with and without a history of early UTI, respectively. Among children with UTIs, 18% of those with VUR and 25% of those without VUR had DES. CONCLUSIONS: Dysfunctional elimination is common in a general pediatric population. Neither UTI nor VUR diagnosed before 2 years of age was associated with DES in school-aged children.
机译：目的：有人指出，生命早期的尿路感染（UTI）易导致功能障碍性消除综合征（DES）。这项研究通过比较两个学龄儿童队列，评估了早期尿路感染，膀胱输尿管反流（VUR）和DES之间的关系。方法：UTI队列（n = 123）包括先前参加过1992年至1997年之间进行的前瞻性治疗试验的儿童。所有儿童均在2岁之前被诊断为发热性UTI。比较队列（n = 125）包括1992年至1997年在急诊科接受发烧评估的儿童，他们的尿液培养结果为阴性。通过让家人完成修订版的功能障碍排行评分系统，比较了两个队列中的功能障碍消除症状。结果：收到来自248名儿童的完整调查表。在这两个队列之间，选定的人口统计学或临床特征没有显着差异。分别有22％和21％的儿童有或没有早期尿路感染史的儿童中都有DES。在患有尿路感染的儿童中，有VUR的儿童为18％，而没有VUR的儿童为25％。结论：功能障碍性消除在普通儿科人群中很常见。 2岁之前被诊断出的UTI和VUR均与学龄儿童的DES无关。

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