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首页> 外文期刊>Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies >Octreotide efficacy in the treatment of chylothoraces following cardiac surgery in infants and children.
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Octreotide efficacy in the treatment of chylothoraces following cardiac surgery in infants and children.

机译：奥曲肽在婴儿和儿童心脏手术后治疗乳糜胸中的功效。

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OBJECTIVE: To examine the efficacy of octreotide in resolving chylothoraces in infants and children following cardiac surgery. DESIGN: Retrospective chart review. SETTING: Pediatric intensive care unit of a tertiary care center. PATIENTS: All children who received octreotide for the treatment of chylothoraces following surgery for congenital heart disease over a 30-month period between 2001-2004. INTERVENTIONS: Octreotide infusion. MEASUREMENTS AND MAIN RESULTS: Eight courses of octreotide treatment were identified in seven patients who met our inclusion criteria. The median duration of therapy was 5 days, and dosing ranged from 1 to 4 microg/kg/hr. Treatment did not result in an overall decrease in average chest tube output after 3 days of therapy. However, in two patients (29%) the chylothoraces ultimately resolved during the octreotide infusion. Treatment was well tolerated, and no serious side effects were noted. CONCLUSION: In contrast to previously published reports, we find octreotide therapy for postoperative chylothoraces to be successful in only a minority of cases.
机译：目的：探讨奥曲肽在心脏手术后解决婴幼儿乳糜中的功效。设计：回顾性图表审查。地点：三级护理中心的儿科重症监护室。患者：2001年至2004年之间的30个月内，因先天性心脏病手术而接受奥曲肽治疗乳糜胸的所有儿童。干预措施：奥曲肽输注。测量和主要结果：在符合我们纳入标准的7例患者中确定了8个疗程的奥曲肽治疗。中位治疗时间为5天，给药剂量为1-4微克/千克/小时。治疗3天后，平均胸总管输出量并未总体下降。然而，在两名患者（29％）中，乳糜泻在奥曲肽输注期间最终消退。治疗耐受性良好，未观察到严重的副作用。结论：与以前发表的报告相反，我们发现奥曲肽治疗乳糜胸的成功仅在少数情况下是成功的。

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