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Treatment of periodontitis as a manifestation of neutropenia with or without systemic antibiotics: A systematic review

机译:有或没有全身抗生素治疗牙周炎作为中性粒细胞减少的表现:系统评价

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摘要

The purposes of this paper were to systematically review the clinical presentations and management of periodontitis patients with neutropenia and present a patient with severe autoimmune neutropenia. Twenty-four case reports describing a total of 33 patients were identified. The reported signs and symptoms occurred in either a generalized or localized pattern. Improvements in periodontal condition were observed in 86% of patients who were administered adjuvant systemic antibiotics compared to 47% of patients who were not given supplemental therapy. Granulocyte-colony stimulating factor was administered to 67% of the neutropenic patients, and both improvement and progression of the hematological condition were monitored. Scaling and root planing, in combination with systemic antibiotics to supplement therapy for the underlying disease, have been successful in most cases.
机译:本文的目的是系统地回顾中性粒细胞减少症的牙周炎患者的临床表现和治疗,并介绍重度自身免疫性中性粒细胞减少症的患者。确定了描述总共33例患者的24例病例报告。报告的体征和症状以普遍或局部的方式发生。服用辅助性全身抗生素的患者中有86%的患者的牙周状况有所改善,而未接受辅助治疗的患者中有47%的患者。向67%的中性粒细胞减少症患者施用了粒细胞集落刺激因子,并监测了血液学状况的改善和进展。在大多数情况下,结垢和根部平整结合系统性抗生素来补充针对潜在疾病的疗法已取得成功。

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