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首页> 外文期刊>Pediatrics international : >Two outbreaks of ESBL-producing Klebsiella pneumoniae in a neonatal intensive care unit
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Two outbreaks of ESBL-producing Klebsiella pneumoniae in a neonatal intensive care unit

机译：新生儿重症监护病房两次爆发ESBL产肺炎克雷伯菌

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摘要

Background In the present study, two epidemic episodes of extended spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae in the neonatal intensive care unit (NICU) were evaluated. Methods Routine and surveillance culture samples were taken from seven neonates with signs of infection in the NICU of Selcuk University Faculty of Medicine between 10 March and 25 April 2011, and between 11 June and 30 September 2011. Results ESBL-producing K. pneumoniae strains were isolated in six different samples (one wound, one blood, and four cerebrospinal fluid cultures) of the three neonates in the first episode and in 11 different samples (seven blood and four cerebrospinal fluid cultures) of the four neonates in the second episode. ESBL-producing K. pneumoniae was isolated from inguinal, axillar region, and stool samples of the nine colonized neonates in the second episode. It was determined on pulse field gel electrophoresis that all strains originated from two clones. Conclusions The deficiencies in the infection control measures in an NICU may transform into an epidemic rapidly. Therefore, periodic training, observation, and monitoring of compliance are important.
机译：背景技术在本研究中，对新生儿重症监护病房（NICU）中产生超广谱β-内酰胺酶（ESBL）的肺炎克雷伯菌的两种流行病进行了评估。方法于2011年3月10日至4月25日以及2011年6月11日至9月30日之间，从塞尔丘克大学医学院新生儿重症监护病房（NICU）中抽取7例有感染迹象的新生儿作为常规和监测培养标本。结果产ESBL的肺炎克雷伯菌菌株为在第一集中的三个新生儿的六个不同样本（一个伤口，一个血液和四个脑脊液培养物中）中分离出了第二个发作中的四个新生儿的11个不同的样本（七个血液和四个脑脊液培养物中）中分离出了它们。在第二集中从九个定居新生儿的腹股沟，腋窝区和粪便样本中分离出产生ESBL的肺炎克雷伯菌。通过脉冲场凝胶电泳确定所有菌株均源自两个克隆。结论新生儿重症监护病房（NICU）中感染控制措施的不足可能会迅速转变为流行病。因此，定期培训，观察和监视依从性很重要。

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