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首页> 外文期刊>Pathobiology: journal of immunopathology, molecular and cellular biology >The periarterial space in the lung: its important role in lung edema, transplantation, and microbial or allergic inflammation.
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The periarterial space in the lung: its important role in lung edema, transplantation, and microbial or allergic inflammation.

机译：肺动脉周围间隙：在肺水肿，移植和微生物或过敏性炎症中起重要作用。

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摘要

In mammal lungs different compartments for leukocytes can be identified during health and disease, e.g. lung interstitium, bronchoalveolar space, the epithelium and lamina propria of the air-conducting part. A so far neglected compartment is the space around the branches of the pulmonary arteries, characterized by a unique architecture of capillaries running in parallel to the pulmonary artery. This compartment - the periarterial space - is described and its physiological and pathophysiological role reviewed. The periarterial space is infiltrated by different leukocyte subsets during edema formation in the early stages of a lung transplant rejection and, in particular, during inflammatory and allergic reactions. The periarterial compartment seems to be of major relevance in all these situations.
机译：在哺乳动物的肺中，可以在健康和疾病期间，例如在健康和疾病期间，识别白细胞的不同区室。肺间质，支气管肺泡间隙，上皮和固有层的导气部分。到目前为止，一个被忽视的隔室是肺动脉分支周围的空间，其特征是与肺动脉平行的毛细管结构独特。描述了该隔室-动脉周围空间，并回顾了其生理和病理生理作用。在肺移植排斥早期的水肿形成过程中，尤其是在炎症和过敏反应过程中，不同的白细胞亚群浸润了动脉周间隙。在所有这些情况下，动脉周腔似乎都具有重要意义。

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