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首页> 外文期刊>Pediatric Hematology and Oncology >Clinical features, treatment responses, and outcome of children with idiopathic thrombocytopenic purpura
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Clinical features, treatment responses, and outcome of children with idiopathic thrombocytopenic purpura

机译:儿童特发性血小板减少性紫癜的临床特征,治疗反应和结局

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摘要

The authors investigated demographics, clinical and laboratory features, treatment responses, and outcomes of 93 children (median age 5 years) admitted for idiopathic thrombocytopenic purpura (ITP). The therapy responses of high-dose methylprednisolone (HDMP) (n = 77) and intravenous immunoglobulin (IVIG) (n = 10) treatments were similar. None of the patients with hemorrhage died. Fifteen patients (16.1%) had progressed into chronic ITP. Seven infants had a probable relationship with vaccination; none of these infants progressed into chronic ITP. In conclusion, the overall prognosis in childhood ITP is good. The therapy responses of HDMP and IVIG treatments are similar. Also, ITP cases who havw vaccination history have a benign course.
机译:作者调查了93名因特发性血小板减少性紫癜(ITP)入院的儿童(中位年龄为5岁)的人口统计学,临床和实验室特征,治疗反应和结局。大剂量甲基强的松龙(HDMP)(n = 77)和静脉注射免疫球蛋白(IVIG)(n = 10)的治疗反应相似。没有出血的患者死亡。 15名患者(16.1%)已发展为慢性ITP。七个婴儿可能与疫苗接种有关;这些婴儿均未进展为慢性ITP。总之,儿童ITP的总体预后良好。 HDMP和IVIG的治疗反应相似。同样,拥有疫苗接种史的ITP病例也有良好的发展过程。

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