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首页> 外文期刊>Perfusion >Does 6% hydroxyethyl starch 130/0.4 impact differently on blood glucose than 4% gelatin in patients receiving open heart surgery?
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Does 6% hydroxyethyl starch 130/0.4 impact differently on blood glucose than 4% gelatin in patients receiving open heart surgery?

机译:在接受心脏直视手术的患者中,6%羟乙基淀粉130 / 0.4对血糖的影响与4%明胶对血糖的影响不同吗?

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Objectives: To investigate whether starch-based colloid may impact differently on blood glucose than a gelatin-based colloid in adult patients receiving open heart surgery.Methods: 70 adult patients scheduled for elective first-time cardiac surgery were enrolled and randomized into two groups. The circuits were primed with either 6% HES 130/0.4 or 4% gelatin. The peak glucose level, incidence of hyperglycemia, glucose variation and glucose level at different time points during operation were compared between the two groups. A p-value ≥ 0.05 was accepted as significant.Results: The peak glucose (150±30mg/dl vs 142±27, p=0.236) and glucose variation demonstrated by standard deviation (26±12mg/dl vs 23±11mg/dl, p=0.202) were comparable between the two groups. Repeated measurement ANOVA revealed that the main effect for artificial colloid was not significant (p=0.349).Conclusions: With the data available, we could not prove that starch-based colloid (HES130) had a different impact on intra-operative blood glucose than a gelatin-based colloid in adult patients receiving open heart surgery.
机译:目的:研究在接受心脏直视手术的成年患者中,淀粉基胶体对血糖的影响是否与明胶基胶体不同。方法:将70例计划进行择期首次心脏手术的成年患者随机分为两组。电路用6%HES 130 / 0.4或4%明胶涂底漆。比较两组患者在手术中不同时间点的峰值血糖水平,高血糖发生率,血糖变化和血糖水平。 p值≥0.05被认为是显着性的。结果:峰值葡萄糖(150±30mg / dl vs 142±27,p = 0.236)和葡萄糖变化以标准偏差表示(26±12mg / dl vs 23±11mg / dl) ,p = 0.202)在两组之间具有可比性。重复测量的方差分析表明,人工胶体的主要作用并不显着(p = 0.349)。结论:利用现有数据,我们不能证明淀粉基胶体(HES130)对术中血糖的影响与术中血糖的影响不同。接受心脏直视手术的成年患者使用的基于明胶的胶体。

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