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Review West Nile virus in North America:perspectives on epidemiology and intervention

机译:回顾北美的西尼罗河病毒:流行病学和干预措施的观点

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摘要

West Nile virus(WNV)invaded New York in 1999 and rapidly swept across the North American continent to the West Coast,north into southern Canada and south into Latin America,with minimal genetic change.Regional epidemics in equities and humans typically have included a year of viral introduction with minimal activity,successful overwintering,explosive amplification to epidemic levels the following year and then rapid subsidence.Overwintering possibly included long-term mosquito or avian infections,continued low-level transmission at southern latitudes and dispersal by south-north migrants.Explosive amplification has been associated with infections in several corvid species and other urban birds that produce elevated viremias capable of efficiently infecting even moderately susceptible mosquito species.Intervention has included mass vaccination of equines,and proactive and reactive mosquito control.Proactive mosquito control in areas with established infrastructure has been successful in reducing case incidence.
机译:西尼罗河病毒(WNV)于1999年入侵纽约,并迅速席卷了北美大陆至西海岸,北至加拿大南部,南至拉丁美洲,但遗传变化极小。股票和人类区域性流行病通常包括一年病毒的导入,活性最小,成功的越冬,次年爆发性扩增至流行水平,然后迅速沉降爆炸性扩增与几种Corvid物种和其他城市鸟类的感染有关,这些鸟类产生的病毒血症能够有效感染甚至是中度易感的蚊子。干预措施包括对马进行大规模疫苗接种以及主动和反应性蚊子控制。已建立的基础架构在减少案件发生率。

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