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首页> 外文期刊>Pest Management Science >Perspective Public safety aspects of pyrethroid insecticides used in West Nile virus-carrying mosquito control
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Perspective Public safety aspects of pyrethroid insecticides used in West Nile virus-carrying mosquito control

机译：透视西尼罗河病毒携带蚊子中使用拟除虫菊酯类杀虫剂的公共安全方面

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摘要

West Nile virus is becoming increasingly prevalent in the USA,causing fever,encephalitis,meningitis and many fatalities.Spread of the disease is reduced by controlling the mosquito vectors by a variety of means,including the use of pyrethroid insecticides,which are currently under scrutiny for potential carcinogenic effects in humans.Pyrethrins and resmethrin,a pyrethroid,have been shown to cause tumours in rat and mouse models respectively.However,the tumours appear to be caused by liver enzyme induction and hypertrophy rather than genotoxicity,and the results are therefore unlikely to be applicable to humans.Nonetheless,for resmethrin,the US Environmental Protection Agency(EPA)has concluded that there is a likely risk of carcinogenicity in humans,requiring the manufacturers to provide more detailed data to prove that it can be used safely in vector control.Reproductive toxicity of resmethrin in the rat is also discussed.
机译：西尼罗河病毒在美国变得越来越普遍，引起发烧，脑炎，脑膜炎和许多死亡。通过多种手段控制蚊媒，包括使用拟除虫菊酯类杀虫剂，目前正在对其进行审查，从而减少了该疾病的传播。菊酯和菊酯菊酯（一种拟除虫菊酯）已分别在大鼠和小鼠模型中引起肿瘤。然而，该肿瘤似乎是由肝酶诱导和肥大而不是遗传毒性引起的，因此得出的结果是但是，对于瑞思麦林，美国环境保护署（EPA）得出结论认为，人体内可能存在致癌性风险，要求制造商提供更详细的数据以证明其可安全用于人类体内。媒介控制。还讨论了瑞思敏在大鼠中的生殖毒性。

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