Insecticidal activity and mode of action of 2,4-diaminopyrimidines

Wierenga JM.; Cullen TG.; Dybas JA.; Henrie RN.; Peake CJ.; Plummer MJ.

首页> 外文期刊>Pest Management Science >Insecticidal activity and mode of action of 2,4-diaminopyrimidines

【24h】

Insecticidal activity and mode of action of 2,4-diaminopyrimidines

机译：2,4-二氨基嘧啶的杀虫活性和作用方式

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Three 2,4-diaminopyrimidines were rested against several insect species. They were active against lepidopteran pests with LC50 values <3 mg liter(-1) for most species tested. They were also active against two-spotted spider mite, Tetranychus urticae, (LC50 10-40mg liter(-1)). Folinate, but not hypoxanthine or thymidine was found to be an effective rescue agent, requiring a concentration of 100 mg liter(-1) diet to rescue half of the intoxicated larvae. The results confirm dihydrofolate reductase to be the site of action for these insecticides and are consistent with the mode of action of folinate rescue in mammals.

机译：三个3，2，4-二氨基嘧啶分别针对几种昆虫。它们对大多数种类的LC50值均小于3 mg升（-1）的鳞翅目害虫具有活性。它们还对二斑叶螨Tetranychus urticae（LC50 10-40mg升（-1））有活性。发现叶酸，但不是次黄嘌呤或胸腺嘧啶是有效的拯救剂，需要以100 mg升（-1）的饮食浓度来拯救一半的陶醉幼虫。结果证实二氢叶酸还原酶是这些杀虫剂的作用位点，并且与哺乳动物中叶酸的拯救作用方式一致。

著录项

来源
《Pest Management Science》 |2000年第3期|共4页
作者
Wierenga JM.; Cullen TG.; Dybas JA.; Henrie RN.; Peake CJ.; Plummer MJ.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类植物保护;
关键词
Dihydrofolate reductase; 2; 4-diaminopyrimidines; Leucovorin;

机译：二氢叶酸还原酶;2;4-二氨基嘧啶;白蛋白;

相似文献

外文文献
中文文献
专利

1. Insecticidal activity and mode of action of 2,4-diaminopyrimidines [J] . Wierenga JM., Cullen TG., Dybas JA., Pest Management Science . 2000,第3期

机译：2,4-二氨基嘧啶的杀虫活性和作用方式
2. Resistance of codling moth, Cydia pomonella (L.) (Lepidoptera: Tortricidae), larvae in Michigan to insecticides with different modes of action and the impact on field residual activity [J] . David Mota-Sanchez, John C Wise, Ryan Vander Poppen Pest Management Science . 2008,第9期

机译：密歇根州的苹果蛾，小dia蛾（鳞翅目：Tortricidae），幼虫对不同作用方式的杀虫剂及其对田间残留活性的影响
3. Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids [J] . Haffez Hesham, Chisholm David R., Tatum Natalie J., Bioorganic and medicinal chemistry . 2018,第8期

机译：通过2,4-二取代的噻唑类吡啶醇的配体 - 受体相互作用结构建模探测生物活性
4. A review of Piper spp. (Piperaceae) phytochemistry, insecticidal activity and mode of action [C] . Ian M. Scott, Helen R. Jensen, Bernard J. R. Philogene the Phytochemical Society of Europe Meeting . 2007

机译：Piper SPP综述。（Piperaceae）植物化学，杀虫活性和行动方式
5. Basis of imazethapyr selectivity in cowpea (Vigna senensis), interactions between insecticides and cytochrome P450 activities, and cytochrome P450 monooxygenase metabolism of imazethapyr. [D] . Baerg, Roger John. 1994

机译：cow豆（Vigna senensis）中咪唑乙烟草选择性的基础，杀虫剂与细胞色素P450活性之间的相互作用以及咪唑乙烟草的细胞色素P450单加氧酶代谢。
6. Attrition physical integrity and insecticidal activity of long-lasting insecticidal nets in sub-Saharan Africa and modelling of their impact on vectorial capacity [O] . Olivier Briet, Hannah Koenker, Laura Norris, 2020

机译：亚撒哈拉以南非洲持久杀虫网的衰减身体完整性和杀虫活性及其对矢量容量的影响
7. PMI Activity TZ-1,2: IRS and LLIN: Integration of Methods and Insecticide Mode of Actions for Control of African Malaria Vector Mosquitoes [O] . Okumu Fredros O, Moore Sarah J 2012

机译：PMI活动TZ-1,2：IRS和LLIN：控制非洲疟疾媒介蚊子的方法和杀虫剂作用模式的整合
8. Examination of the Proconvulsant Actions of Pyrethroid Insecticides Using Pentylenetetrazol and Amygdala Kindling Seizure Models [R] . Gilbert, M. E., Acheson, S. K., Mack, C. M., 1990

机译：用戊四唑和杏仁核点燃癫痫发作模型检测拟除虫菊酯类杀虫剂的惊厥作用

Insecticidal activity and mode of action of 2,4-diaminopyrimidines

摘要

著录项

相似文献

相关主题

期刊订阅