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首页> 外文期刊>Pharmaceutical Chemistry Journal >ISOLATION AND CHARACTERIZATION OF A NEW ANTICANCER DITERPENOID FROM JATROPHA GOSSYPIFOLIA
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ISOLATION AND CHARACTERIZATION OF A NEW ANTICANCER DITERPENOID FROM JATROPHA GOSSYPIFOLIA

机译：麻疯树新抗癌药二萜的分离与鉴定

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摘要

Jatropha gossypifolia root bark is used in ethnomedicine for the treatment of various diseases and infections. We have studied the phytochemistry and evaluated the anticancer activity of J. gossypifolia root extract. Phytochemical investigation of the root of J. gossypifolia resulted in the isolation and characterization of one new diterpenoid along with four well-known compounds. The new compound was established by 1D and 2D NMR spectra and x-ray analysis, while spectral (~1H, ~(13)C NMR, and ESI-MS) characteristics of the known compounds were compared with reported data. The new compound showed potent proliferation inhibitory activity against A-549 human cancer cell line.
机译：麻风树棉根皮用于民族药中，用于治疗各种疾病和感染。我们已经研究了棉铃兰根提取物的植物化学并评估了其抗癌活性。对棉铃虫根的植物化学研究导致一种新的二萜与四种众所周知的化合物的分离和鉴定。通过1D和2D NMR光谱和X射线分析建立了新化合物，同时将已知化合物的光谱（〜1H，〜（13）C NMR和ESI-MS）特征与报道的数据进行了比较。新化合物对A-549人癌细胞系显示出有效的增殖抑制活性。

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